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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM183B
All Species:
20
Human Site:
S336
Identified Species:
55
UniProt:
Q1AE95
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q1AE95
NP_001073277.1
376
42940
S336
V
R
L
V
F
Q
D
S
P
V
H
G
G
R
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537117
376
42773
S336
V
R
L
V
F
Q
D
S
P
V
H
G
G
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJB9
375
42927
S335
V
R
L
V
F
Q
D
S
P
V
R
G
G
Q
N
Rat
Rattus norvegicus
Q68FS7
376
42963
S336
V
R
L
V
F
Q
D
S
P
V
R
G
G
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521516
353
40327
S313
V
R
L
V
F
Q
D
S
P
I
Q
N
G
R
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001014317
364
41552
S320
V
R
L
E
F
Q
D
S
P
M
I
R
G
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392998
225
26552
H186
A
C
V
I
R
T
L
H
Y
T
Y
F
A
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188636
392
45277
G330
H
R
V
K
L
E
F
G
R
K
G
R
R
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001168843
236
26265
R197
P
E
S
M
E
K
L
R
C
L
R
A
C
V
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
95.4
N.A.
91.7
93.3
N.A.
84.3
N.A.
N.A.
63.8
N.A.
N.A.
22
N.A.
25.7
Protein Similarity:
100
N.A.
N.A.
97.8
N.A.
94.6
96
N.A.
88.3
N.A.
N.A.
76
N.A.
N.A.
37.5
N.A.
44.6
P-Site Identity:
100
N.A.
N.A.
100
N.A.
80
80
N.A.
80
N.A.
N.A.
66.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
86.6
86.6
N.A.
86.6
N.A.
N.A.
80
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
58.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
60.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
12
0
0
0
12
0
0
% C
% Asp:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
12
12
12
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
67
0
12
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
12
45
67
12
0
% G
% His:
12
0
0
0
0
0
0
12
0
0
23
0
0
0
12
% H
% Ile:
0
0
0
12
0
0
0
0
0
12
12
0
0
0
12
% I
% Lys:
0
0
0
12
0
12
0
0
0
12
0
0
0
12
56
% K
% Leu:
0
0
67
0
12
0
23
0
0
12
0
0
0
12
12
% L
% Met:
0
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% N
% Pro:
12
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
67
0
0
0
0
12
0
0
23
0
% Q
% Arg:
0
78
0
0
12
0
0
12
12
0
34
23
12
34
0
% R
% Ser:
0
0
12
0
0
0
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% T
% Val:
67
0
23
56
0
0
0
0
0
45
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _