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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC5A12
All Species:
20
Human Site:
Y608
Identified Species:
40
UniProt:
Q1EHB4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q1EHB4
NP_848593.2
618
67647
Y608
Y
D
P
K
D
K
S
Y
N
N
M
A
F
E
T
Chimpanzee
Pan troglodytes
XP_508335
618
67644
Y608
Y
D
P
K
D
K
S
Y
N
N
M
A
F
E
T
Rhesus Macaque
Macaca mulatta
XP_001090490
700
76564
Y690
Y
D
P
K
D
K
S
Y
N
N
M
A
F
E
I
Dog
Lupus familis
XP_534095
627
68528
F616
H
D
P
K
D
K
S
F
H
T
T
A
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q49B93
619
67933
Y608
Y
N
P
K
E
K
S
Y
S
N
S
V
P
E
K
Rat
Rattus norvegicus
Q63008
618
65178
Y609
G
A
E
T
H
P
L
Y
L
G
H
D
V
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511285
629
68531
Y618
Y
N
P
S
D
K
S
Y
T
N
M
E
S
D
K
Chicken
Gallus gallus
XP_428889
629
69078
Y620
Y
N
P
E
E
K
S
Y
T
N
M
S
K
E
S
Frog
Xenopus laevis
Q7SYH5
622
67537
F603
Q
G
T
D
N
P
A
F
N
N
M
E
M
T
S
Zebra Danio
Brachydanio rerio
Q7T384
623
67302
N614
T
N
A
G
F
D
H
N
E
T
S
I
V
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83740
604
66569
E594
T
A
P
P
R
L
D
E
I
E
W
E
K
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785969
626
68017
E617
H
A
P
K
S
Q
E
E
P
H
T
T
M
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
85.1
85.4
N.A.
85.3
46.2
N.A.
81.7
70.5
53.7
66.1
N.A.
36.5
N.A.
N.A.
45
Protein Similarity:
100
99.6
87
90.1
N.A.
93.2
64.5
N.A.
89.5
84.4
70.7
77
N.A.
53.7
N.A.
N.A.
63.9
P-Site Identity:
100
100
93.3
53.3
N.A.
53.3
20
N.A.
53.3
53.3
20
0
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
73.3
N.A.
73.3
20
N.A.
66.6
86.6
46.6
13.3
N.A.
6.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
9
0
0
0
9
0
0
0
0
34
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
34
0
9
42
9
9
0
0
0
0
9
0
9
0
% D
% Glu:
0
0
9
9
17
0
9
17
9
9
0
25
0
67
0
% E
% Phe:
0
0
0
0
9
0
0
17
0
0
0
0
25
0
0
% F
% Gly:
9
9
0
9
0
0
0
0
0
9
0
0
0
0
0
% G
% His:
17
0
0
0
9
0
9
0
9
9
9
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
9
% I
% Lys:
0
0
0
50
0
59
0
0
0
0
0
0
17
0
42
% K
% Leu:
0
0
0
0
0
9
9
0
9
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
50
0
17
0
0
% M
% Asn:
0
34
0
0
9
0
0
9
34
59
0
0
0
0
0
% N
% Pro:
0
0
75
9
0
17
0
0
9
0
0
0
9
0
0
% P
% Gln:
9
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
9
0
59
0
9
0
17
9
9
0
17
% S
% Thr:
17
0
9
9
0
0
0
0
17
17
17
9
0
9
25
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
50
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _