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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOXA1
All Species:
22.42
Human Site:
Y307
Identified Species:
44.85
UniProt:
Q1HG43
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q1HG43
NP_653166.2
343
37815
Y307
G
G
L
L
S
P
R
Y
R
S
M
A
D
S
P
Chimpanzee
Pan troglodytes
XP_001162967
343
37755
Y307
G
G
L
L
S
P
R
Y
R
S
M
A
D
S
P
Rhesus Macaque
Macaca mulatta
XP_001111148
298
32938
S268
R
Y
R
S
V
A
D
S
P
E
P
Q
D
I
P
Dog
Lupus familis
XP_544660
342
37605
Y307
G
G
L
L
S
P
R
Y
R
S
T
A
E
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE49
341
37576
Y306
G
G
L
L
S
P
H
Y
R
S
I
A
E
S
P
Rat
Rattus norvegicus
NP_001101237
340
37554
Y305
G
G
L
L
S
P
H
Y
R
S
I
A
E
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518653
325
35246
P294
Q
R
G
E
A
E
G
P
P
P
R
A
Y
S
N
Chicken
Gallus gallus
XP_425054
322
36243
Y292
H
E
N
K
A
E
D
Y
R
E
M
T
E
V
Y
Frog
Xenopus laevis
Q6DDK3
308
34950
Q277
K
T
Q
P
K
V
L
Q
L
I
F
S
Y
G
E
Zebra Danio
Brachydanio rerio
XP_002666953
346
38430
T312
G
V
I
H
D
D
V
T
P
A
E
N
N
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609733
474
53330
S317
R
Y
R
K
P
R
N
S
R
S
L
E
D
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34298
397
43783
K342
K
N
D
I
S
S
D
K
T
A
G
S
S
G
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
82.5
87.4
N.A.
82.5
81.9
N.A.
52.4
42.2
43.1
39.3
N.A.
25.7
N.A.
27.7
N.A.
Protein Similarity:
100
99.4
84.2
90.9
N.A.
88.6
88.6
N.A.
65.8
60.9
62
60.1
N.A.
38.1
N.A.
43.5
N.A.
P-Site Identity:
100
100
13.3
86.6
N.A.
80
80
N.A.
13.3
20
0
13.3
N.A.
26.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
13.3
93.3
N.A.
93.3
93.3
N.A.
20
33.3
6.6
33.3
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
9
0
0
0
17
0
50
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
9
25
0
0
0
0
0
34
0
0
% D
% Glu:
0
9
0
9
0
17
0
0
0
17
9
9
34
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% F
% Gly:
50
42
9
0
0
0
9
0
0
0
9
0
0
17
0
% G
% His:
9
0
0
9
0
0
17
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
0
0
0
0
9
17
0
0
9
0
% I
% Lys:
17
0
0
17
9
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
42
42
0
0
9
0
9
0
9
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
9
0
0
0
0
9
9
0
9
% N
% Pro:
0
0
0
9
9
42
0
9
25
9
9
0
0
9
59
% P
% Gln:
9
0
9
0
0
0
0
9
0
0
0
9
0
0
0
% Q
% Arg:
17
9
17
0
0
9
25
0
59
0
9
0
0
0
0
% R
% Ser:
0
0
0
9
50
9
0
17
0
50
0
17
9
59
0
% S
% Thr:
0
9
0
0
0
0
0
9
9
0
9
9
0
0
0
% T
% Val:
0
9
0
0
9
9
9
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
50
0
0
0
0
17
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _