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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUOXA2 All Species: 25.45
Human Site: S165 Identified Species: 62.22
UniProt: Q1HG44 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q1HG44 NP_997464.2 320 34787 S165 A E K F T P S S P C G L Y H Q
Chimpanzee Pan troglodytes XP_001146826 202 22328 L54 G H S R W F W L V R V L L S L
Rhesus Macaque Macaca mulatta XP_001111110 320 34767 S165 A E K F T P S S P C G L Y H Q
Dog Lupus familis XP_851517 320 34889 S165 A E K F T P S S P C G L Y R Q
Cat Felis silvestris
Mouse Mus musculus Q9D311 320 35409 S165 A E K F T P S S P C G L Y H Q
Rat Rattus norvegicus XP_575222 320 35553 S165 A E K F T P N S P C G L Y H Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518653 325 35246 S165 A E K F S P P S P C G L H Q Q
Chicken Gallus gallus XP_425054 322 36243 S165 A E K F T T Q S P C N V H R Q
Frog Xenopus laevis Q6DDK3 308 34950 T160 V Y V A E K F T I S S D C G L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34298 397 43783 V165 L P Y P M L S V L E Y F S L N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.9 94.3 83.4 N.A. 78.7 78.1 N.A. 66.4 45.9 40.6 N.A. N.A. N.A. N.A. 25.1 N.A.
Protein Similarity: 100 49.6 97.1 87.5 N.A. 85 84 N.A. 74.4 64.5 61.2 N.A. N.A. N.A. N.A. 39.7 N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 100 93.3 N.A. 73.3 60 0 N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 6.6 100 93.3 N.A. 100 100 N.A. 86.6 73.3 6.6 N.A. N.A. N.A. N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 70 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 70 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 70 0 0 10 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 70 0 10 10 0 0 0 0 10 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 60 0 0 10 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 20 40 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 70 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 10 0 10 10 0 0 70 10 10 20 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 10 % N
% Pro: 0 10 0 10 0 60 10 0 70 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 70 % Q
% Arg: 0 0 0 10 0 0 0 0 0 10 0 0 0 20 0 % R
% Ser: 0 0 10 0 10 0 50 70 0 10 10 0 10 10 0 % S
% Thr: 0 0 0 0 60 10 0 10 0 0 0 0 0 0 0 % T
% Val: 10 0 10 0 0 0 0 10 10 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 0 0 0 0 0 0 0 10 0 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _