KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOXA2
All Species:
10.61
Human Site:
S285
Identified Species:
25.93
UniProt:
Q1HG44
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q1HG44
NP_997464.2
320
34787
S285
L
R
T
L
L
D
Q
S
A
K
D
C
S
Q
E
Chimpanzee
Pan troglodytes
XP_001146826
202
22328
L174
L
P
D
P
V
L
Y
L
A
E
K
F
T
P
S
Rhesus Macaque
Macaca mulatta
XP_001111110
320
34767
S285
L
R
T
L
L
D
Q
S
A
E
D
C
S
Q
A
Dog
Lupus familis
XP_851517
320
34889
S285
L
R
T
F
L
D
Q
S
V
K
N
Y
G
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D311
320
35409
S285
L
R
S
F
L
D
L
S
V
K
D
C
S
N
Q
Rat
Rattus norvegicus
XP_575222
320
35553
N285
L
R
A
L
L
D
Q
N
V
K
D
C
S
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518653
325
35246
E285
A
F
L
D
L
S
G
E
D
Q
R
G
E
A
E
Chicken
Gallus gallus
XP_425054
322
36243
H285
L
K
T
F
F
D
L
H
E
N
K
A
E
D
Y
Frog
Xenopus laevis
Q6DDK3
308
34950
F280
P
K
V
L
Q
L
I
F
S
Y
G
E
E
E
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34298
397
43783
W285
G
L
G
I
C
E
H
W
R
I
Y
T
L
S
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.9
94.3
83.4
N.A.
78.7
78.1
N.A.
66.4
45.9
40.6
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
100
49.6
97.1
87.5
N.A.
85
84
N.A.
74.4
64.5
61.2
N.A.
N.A.
N.A.
N.A.
39.7
N.A.
P-Site Identity:
100
13.3
86.6
53.3
N.A.
60
66.6
N.A.
13.3
20
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
33.3
93.3
66.6
N.A.
73.3
80
N.A.
20
26.6
33.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
30
0
0
10
0
10
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
40
0
0
0
% C
% Asp:
0
0
10
10
0
60
0
0
10
0
40
0
0
10
10
% D
% Glu:
0
0
0
0
0
10
0
10
10
20
0
10
30
10
20
% E
% Phe:
0
10
0
30
10
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
10
0
10
0
0
0
10
0
0
0
10
10
10
0
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% I
% Lys:
0
20
0
0
0
0
0
0
0
40
20
0
0
0
0
% K
% Leu:
70
10
10
40
60
20
20
10
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
10
0
0
20
0
% N
% Pro:
10
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
0
40
0
0
10
0
0
0
20
30
% Q
% Arg:
0
50
0
0
0
0
0
0
10
0
10
0
0
0
0
% R
% Ser:
0
0
10
0
0
10
0
40
10
0
0
0
40
20
10
% S
% Thr:
0
0
40
0
0
0
0
0
0
0
0
10
10
0
10
% T
% Val:
0
0
10
0
10
0
0
0
30
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
10
10
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _