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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM110C
All Species:
14.24
Human Site:
T283
Identified Species:
34.81
UniProt:
Q1W6H9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q1W6H9
NP_001071178.1
321
33863
T283
L
I
E
Q
V
P
S
T
T
S
V
I
E
R
N
Chimpanzee
Pan troglodytes
XP_515269
321
33848
T283
L
I
E
Q
V
P
S
T
T
S
V
I
E
R
N
Rhesus Macaque
Macaca mulatta
XP_001095542
320
33975
T282
L
I
E
Q
V
P
S
T
T
S
V
I
E
R
N
Dog
Lupus familis
XP_848273
334
36108
T296
G
L
Q
E
E
E
L
T
E
Q
V
P
S
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE94
421
45300
S359
C
V
T
L
K
V
R
S
V
S
M
A
A
S
D
Rat
Rattus norvegicus
Q5RKJ0
326
35560
L288
G
L
Q
E
E
E
L
L
E
Q
V
P
S
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516896
415
45118
G326
L
A
E
Q
V
S
P
G
P
S
V
I
E
R
N
Chicken
Gallus gallus
XP_417749
345
36952
E306
G
E
D
A
G
P
G
E
E
E
P
D
T
R
L
Frog
Xenopus laevis
NP_001089869
300
33115
E256
Q
F
S
E
T
T
A
E
E
T
P
A
K
R
L
Zebra Danio
Brachydanio rerio
Q4QRD7
397
42933
S336
I
V
S
L
N
F
R
S
A
S
M
I
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.3
43.4
N.A.
52.9
61.9
N.A.
42.6
33.3
31.1
28.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
95.9
51.2
N.A.
58.9
69
N.A.
53.9
46.3
43.9
43.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
6.6
6.6
N.A.
66.6
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
26.6
N.A.
66.6
20
33.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
10
0
10
0
0
20
10
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
20
% D
% Glu:
0
10
40
30
20
20
0
20
40
10
0
0
40
0
0
% E
% Phe:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
30
0
0
0
10
0
10
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
30
0
0
0
0
0
0
0
0
0
50
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
40
20
0
20
0
0
20
10
0
0
0
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
40
% N
% Pro:
0
0
0
0
0
40
10
0
10
0
20
20
0
0
0
% P
% Gln:
10
0
20
40
0
0
0
0
0
20
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
20
0
0
0
0
0
0
60
0
% R
% Ser:
0
0
20
0
0
10
30
20
0
60
0
0
30
20
0
% S
% Thr:
0
0
10
0
10
10
0
40
30
10
0
0
10
20
20
% T
% Val:
0
20
0
0
40
10
0
0
10
0
60
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _