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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INF2 All Species: 16.97
Human Site: S263 Identified Species: 46.67
UniProt: Q27J81 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q27J81 NP_001026884.3 1249 135624 S263 E E E L L R V S G G V D M S S
Chimpanzee Pan troglodytes XP_510196 1247 135314 S263 E E E L L R V S G G V D M S S
Rhesus Macaque Macaca mulatta XP_001094595 1134 124027 R234 L D V L A R L R D L E D A D L
Dog Lupus familis XP_547999 1094 119278 T231 L Q L L D I L T R L R D L E D
Cat Felis silvestris
Mouse Mus musculus Q0GNC1 1273 138542 S263 E E E L Q R I S D G I N M N S
Rat Rattus norvegicus XP_001072750 1003 111405 S179 C S Q Q Y R F S V I M N E L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521330 870 94662 S46 I R L L Q I P S V V N Y S G L
Chicken Gallus gallus
Frog Xenopus laevis Q6NTV6 1099 121463 Y263 E E E L L K I Y G G I N M N N
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785094 1472 159223 D277 E L M S Y Y P D D G V D L N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 87.2 65.3 N.A. 78.6 67.4 N.A. 38.2 N.A. 52.4 N.A. N.A. N.A. N.A. N.A. 33.6
Protein Similarity: 100 99.1 88.1 71.2 N.A. 84.2 72.1 N.A. 48.9 N.A. 65.8 N.A. N.A. N.A. N.A. N.A. 50.2
P-Site Identity: 100 100 20 13.3 N.A. 60 20 N.A. 13.3 N.A. 53.3 N.A. N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 33.3 40 N.A. 86.6 40 N.A. 13.3 N.A. 93.3 N.A. N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 0 0 0 0 0 0 12 0 0 % A
% Cys: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 12 0 0 12 34 0 0 56 0 12 12 % D
% Glu: 56 45 45 0 0 0 0 0 0 0 12 0 12 12 0 % E
% Phe: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 34 56 0 0 0 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 23 23 0 0 12 23 0 0 0 0 % I
% Lys: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % K
% Leu: 23 12 23 78 34 0 23 0 0 23 0 0 23 12 23 % L
% Met: 0 0 12 0 0 0 0 0 0 0 12 0 45 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 12 34 0 34 12 % N
% Pro: 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % P
% Gln: 0 12 12 12 23 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 12 0 0 0 56 0 12 12 0 12 0 0 0 0 % R
% Ser: 0 12 0 12 0 0 0 56 0 0 0 0 12 23 56 % S
% Thr: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % T
% Val: 0 0 12 0 0 0 23 0 23 12 34 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 23 12 0 12 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _