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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INF2
All Species:
7.58
Human Site:
S586
Identified Species:
20.83
UniProt:
Q27J81
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q27J81
NP_001026884.3
1249
135624
S586
E
H
N
S
M
W
A
S
L
S
S
P
D
A
E
Chimpanzee
Pan troglodytes
XP_510196
1247
135314
S584
E
H
N
S
M
W
A
S
L
S
S
P
D
A
E
Rhesus Macaque
Macaca mulatta
XP_001094595
1134
124027
P510
P
A
A
K
P
K
E
P
T
T
A
A
A
P
A
Dog
Lupus familis
XP_547999
1094
119278
C509
C
Y
Q
L
R
V
E
C
M
L
L
C
E
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q0GNC1
1273
138542
T621
E
R
N
S
M
W
A
T
L
G
S
P
C
T
A
Rat
Rattus norvegicus
XP_001072750
1003
111405
L452
E
K
H
E
I
E
N
L
R
A
F
T
E
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521330
870
94662
V319
W
E
A
L
E
I
L
V
N
R
A
V
L
L
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NTV6
1099
121463
G486
P
P
P
P
P
L
P
G
M
G
G
M
L
P
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785094
1472
159223
R571
G
P
N
R
N
I
W
R
Q
I
S
E
H
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
87.2
65.3
N.A.
78.6
67.4
N.A.
38.2
N.A.
52.4
N.A.
N.A.
N.A.
N.A.
N.A.
33.6
Protein Similarity:
100
99.1
88.1
71.2
N.A.
84.2
72.1
N.A.
48.9
N.A.
65.8
N.A.
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
100
0
0
N.A.
60
6.6
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
20
N.A.
66.6
33.3
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
23
0
0
0
34
0
0
12
23
12
12
23
34
% A
% Cys:
12
0
0
0
0
0
0
12
0
0
0
12
12
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
23
12
0
% D
% Glu:
45
12
0
12
12
12
23
0
0
0
0
12
23
0
23
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
12
0
23
12
0
0
23
0
% G
% His:
0
23
12
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
12
23
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
12
0
12
0
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
23
0
12
12
12
34
12
12
0
23
12
0
% L
% Met:
0
0
0
0
34
0
0
0
23
0
0
12
0
0
0
% M
% Asn:
0
0
45
0
12
0
12
0
12
0
0
0
0
0
0
% N
% Pro:
23
23
12
12
23
0
12
12
0
0
0
34
0
23
12
% P
% Gln:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
12
0
12
12
0
0
12
12
12
0
0
0
0
12
% R
% Ser:
0
0
0
34
0
0
0
23
0
23
45
0
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
12
12
12
0
12
0
12
12
% T
% Val:
0
0
0
0
0
12
0
12
0
0
0
12
0
0
0
% V
% Trp:
12
0
0
0
0
34
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _