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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDS5A
All Species:
17.88
Human Site:
S1223
Identified Species:
35.76
UniProt:
Q29RF7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q29RF7
NP_056015.2
1337
150830
S1223
V
K
N
K
E
I
N
S
D
Q
A
T
Q
G
N
Chimpanzee
Pan troglodytes
XP_526554
1419
159452
S1305
V
K
N
K
E
I
N
S
D
Q
A
T
Q
G
N
Rhesus Macaque
Macaca mulatta
XP_001118201
1528
173307
K1293
L
V
R
S
E
L
E
K
P
R
G
R
K
K
T
Dog
Lupus familis
XP_851177
1337
150801
S1223
V
K
N
K
E
I
N
S
D
Q
T
T
Q
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6A026
1332
150310
S1222
V
K
N
K
E
I
N
S
D
Q
S
T
Q
G
N
Rat
Rattus norvegicus
A4L9P7
1333
150268
S1222
V
K
N
K
E
I
N
S
D
Q
S
T
Q
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512499
1369
153722
D1255
K
N
K
E
M
N
S
D
Q
A
A
Q
G
N
I
Chicken
Gallus gallus
Q5F3V3
1330
150113
D1217
K
N
K
E
I
N
S
D
Q
A
T
Q
G
N
S
Frog
Xenopus laevis
Q4KLU7
1323
149509
A1214
E
V
N
L
D
Q
T
A
P
S
N
T
G
T
E
Zebra Danio
Brachydanio rerio
A1L1F4
1320
148940
A1222
G
R
K
R
A
A
P
A
S
D
G
T
E
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623860
1203
137941
A1121
N
T
R
N
Y
L
P
A
E
M
Q
I
N
M
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790621
1624
181368
E1290
A
V
A
R
S
S
S
E
D
S
Q
S
P
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.7
61.3
98.8
N.A.
97.4
97.8
N.A.
89.8
92.6
86.6
81
N.A.
N.A.
37.7
N.A.
39.2
Protein Similarity:
100
93.9
73.6
99.3
N.A.
98.4
98.6
N.A.
92.8
95.4
92.2
88.1
N.A.
N.A.
58.2
N.A.
56.9
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
6.6
0
13.3
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
33.3
93.3
N.A.
100
100
N.A.
20
20
26.6
40
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
9
0
25
0
17
25
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
17
50
9
0
0
0
0
0
% D
% Glu:
9
0
0
17
50
0
9
9
9
0
0
0
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
17
0
25
42
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
42
0
0
0
0
0
9
0
0
9
% I
% Lys:
17
42
25
42
0
0
0
9
0
0
0
0
9
9
0
% K
% Leu:
9
0
0
9
0
17
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
9
0
0
0
0
9
0
0
0
9
0
% M
% Asn:
9
17
50
9
0
17
42
0
0
0
9
0
9
25
42
% N
% Pro:
0
0
0
0
0
0
17
0
17
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
17
42
17
17
42
0
0
% Q
% Arg:
0
9
17
17
0
0
0
0
0
9
0
9
0
0
0
% R
% Ser:
0
0
0
9
9
9
25
42
9
17
17
9
0
0
25
% S
% Thr:
0
9
0
0
0
0
9
0
0
0
17
59
0
9
9
% T
% Val:
42
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _