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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLEC16A All Species: 16.97
Human Site: S356 Identified Species: 41.48
UniProt: Q2KHT3 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2KHT3 NP_056041.1 1053 117715 S356 T E Q D I Q R S S A K P S I R
Chimpanzee Pan troglodytes XP_001141543 1053 117666 S356 T E Q D I Q R S S A K P S I R
Rhesus Macaque Macaca mulatta XP_001104364 1052 117480 S356 T E Q D V Q R S S A K P S I R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q80U30 1036 116214 S356 P A Q D V P R S S A K P S I R
Rat Rattus norvegicus XP_213209 1050 117382 S356 P A Q D A P R S S A K P S I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509427 1030 117294 F356 D K T A V P Y F S N L V W F I
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002661217 900 100462 K265 D E G P E E E K E K A K G T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393990 1005 114418 K352 T I Q T G A S K V L E M Y G D
Nematode Worm Caenorhab. elegans P46578 892 100843 Y257 D L I D L I H Y I G E L L D V
Sea Urchin Strong. purpuratus XP_001176503 739 84126 L104 N E T S L Y Y L L S N N H V N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.3 N.A. N.A. 89.7 90.9 N.A. 74.1 N.A. N.A. 58.1 N.A. N.A. 49.3 32.1 41.9
Protein Similarity: 100 99.9 98.2 N.A. N.A. 92.7 94 N.A. 79.1 N.A. N.A. 66.9 N.A. N.A. 66.1 47.4 53.3
P-Site Identity: 100 100 93.3 N.A. N.A. 73.3 73.3 N.A. 6.6 N.A. N.A. 6.6 N.A. N.A. 13.3 6.6 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 80 73.3 N.A. 20 N.A. N.A. 13.3 N.A. N.A. 20 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 10 10 10 0 0 0 50 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 30 0 0 60 0 0 0 0 0 0 0 0 0 10 10 % D
% Glu: 0 50 0 0 10 10 10 0 10 0 20 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % F
% Gly: 0 0 10 0 10 0 0 0 0 10 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % H
% Ile: 0 10 10 0 20 10 0 0 10 0 0 0 0 50 10 % I
% Lys: 0 10 0 0 0 0 0 20 0 10 50 10 0 0 0 % K
% Leu: 0 10 0 0 20 0 0 10 10 10 10 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 10 10 10 0 0 10 % N
% Pro: 20 0 0 10 0 30 0 0 0 0 0 50 0 0 0 % P
% Gln: 0 0 60 0 0 30 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 50 % R
% Ser: 0 0 0 10 0 0 10 50 60 10 0 0 50 0 0 % S
% Thr: 40 0 20 10 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 30 0 0 0 10 0 0 10 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 10 20 10 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _