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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLEC16A
All Species:
18.48
Human Site:
Y219
Identified Species:
45.19
UniProt:
Q2KHT3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2KHT3
NP_056041.1
1053
117715
Y219
R
D
K
T
A
V
P
Y
F
S
N
L
V
W
F
Chimpanzee
Pan troglodytes
XP_001141543
1053
117666
Y219
R
D
K
T
A
V
P
Y
F
S
N
L
V
W
F
Rhesus Macaque
Macaca mulatta
XP_001104364
1052
117480
Y219
R
D
K
T
A
V
P
Y
F
S
N
L
V
W
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q80U30
1036
116214
Y219
R
D
K
T
A
V
P
Y
F
S
N
L
V
W
F
Rat
Rattus norvegicus
XP_213209
1050
117382
Y219
R
D
K
T
A
V
P
Y
F
S
N
L
V
W
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509427
1030
117294
F216
L
E
K
N
M
F
V
F
F
L
N
I
L
R
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002661217
900
100462
D129
I
N
C
E
F
L
N
D
V
L
T
D
H
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393990
1005
114418
S217
R
T
A
A
P
Y
F
S
N
L
V
W
F
I
G
Nematode Worm
Caenorhab. elegans
P46578
892
100843
I122
S
N
N
H
V
N
S
I
I
S
H
K
F
D
L
Sea Urchin
Strong. purpuratus
XP_001176503
739
84126
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.3
N.A.
N.A.
89.7
90.9
N.A.
74.1
N.A.
N.A.
58.1
N.A.
N.A.
49.3
32.1
41.9
Protein Similarity:
100
99.9
98.2
N.A.
N.A.
92.7
94
N.A.
79.1
N.A.
N.A.
66.9
N.A.
N.A.
66.1
47.4
53.3
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
20
N.A.
N.A.
0
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
46.6
N.A.
N.A.
13.3
N.A.
N.A.
6.6
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
50
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
0
0
0
0
0
10
0
0
0
10
0
10
0
% D
% Glu:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
10
10
10
60
0
0
0
20
0
50
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
10
0
0
10
0
10
0
% I
% Lys:
0
0
60
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
10
0
0
0
0
10
0
0
0
30
0
50
10
10
20
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
10
10
0
10
10
0
10
0
60
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
50
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
60
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
10
0
0
0
0
0
10
10
0
60
0
0
0
0
0
% S
% Thr:
0
10
0
50
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
10
50
10
0
10
0
10
0
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
50
0
% W
% Tyr:
0
0
0
0
0
10
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _