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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 20.61
Human Site: Y405 Identified Species: 75.56
UniProt: Q2L4Q9 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2L4Q9 NP_001034592.1 553 58410 Y405 L R P L C L P Y P D H H L P D
Chimpanzee Pan troglodytes XP_001156750 553 58309 Y405 L R P L C L P Y A D H H L P D
Rhesus Macaque Macaca mulatta XP_001112012 553 58477 Y405 L R P L C L P Y A D H H L P D
Dog Lupus familis XP_547043 551 58886 Y405 L R P L C L P Y S D H H L P D
Cat Felis silvestris
Mouse Mus musculus Q571E5 552 58956 Y405 L R P L C L P Y A D H H L P D
Rat Rattus norvegicus Q5K2P9 875 94464 H451 P S A V C L P H H E H Y F L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515473 578 61007 Y411 L R P L C L P Y A S H R L P E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.3 85.7 N.A. 81 26.9 N.A. 66.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 97.4 89.5 N.A. 86.4 36.7 N.A. 75.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 93.3 N.A. 93.3 26.6 N.A. 73.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 93.3 53.3 N.A. 80 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 0 0 0 0 0 58 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 72 0 0 0 0 72 % D
% Glu: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 15 15 0 100 72 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 86 0 0 86 0 100 0 0 0 0 0 0 86 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 0 86 0 0 0 100 0 15 0 0 0 0 86 15 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 86 0 0 0 0 0 0 0 0 0 15 0 0 0 % R
% Ser: 0 15 0 0 0 0 0 0 15 15 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 86 0 0 0 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _