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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF423
All Species:
30
Human Site:
S375
Identified Species:
66
UniProt:
Q2M1K9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M1K9
NP_055884.2
1284
144605
S375
S
S
A
T
P
D
S
S
A
S
V
E
R
G
S
Chimpanzee
Pan troglodytes
XP_520629
1284
144557
S375
S
S
A
T
P
D
S
S
A
S
V
E
R
G
S
Rhesus Macaque
Macaca mulatta
XP_001082640
1292
145402
S375
S
S
A
T
P
D
S
S
A
S
V
E
R
G
S
Dog
Lupus familis
XP_544417
1056
117944
R229
F
C
D
K
S
F
I
R
L
S
Y
L
K
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q80TS5
1292
145332
S383
S
S
A
T
P
D
S
S
A
S
V
E
R
G
S
Rat
Rattus norvegicus
O08961
1311
147208
T383
S
S
A
T
P
D
S
T
P
D
P
V
L
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507176
1315
146321
S362
S
S
A
T
P
D
S
S
A
S
A
E
R
G
S
Chicken
Gallus gallus
XP_414103
1284
145511
S372
S
S
A
T
P
D
S
S
A
S
V
E
R
G
S
Frog
Xenopus laevis
Q6NUD7
1310
148622
N363
S
S
T
T
P
D
S
N
L
S
V
D
S
S
T
Zebra Danio
Brachydanio rerio
A1L1R6
1365
151446
S398
S
S
A
T
P
D
S
S
A
S
L
E
R
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z9R4
1228
134159
F392
C
E
Y
C
T
M
K
F
G
N
I
A
G
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97.1
73
N.A.
97.5
95.7
N.A.
86.3
92.5
62.8
77.1
N.A.
22.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
98
73.6
N.A.
98.4
96.8
N.A.
90.1
96.2
75.8
85.8
N.A.
36.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
60
N.A.
93.3
100
53.3
93.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
66.6
N.A.
93.3
100
73.3
100
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
73
0
0
0
0
0
64
0
10
10
0
0
0
% A
% Cys:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
82
0
0
0
10
0
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
64
0
0
0
% E
% Phe:
10
0
0
0
0
10
0
10
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
10
73
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
10
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
19
0
10
10
10
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
82
0
0
0
10
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
64
10
0
% R
% Ser:
82
82
0
0
10
0
82
64
0
82
0
0
10
10
73
% S
% Thr:
0
0
10
82
10
0
0
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
55
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _