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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF7 All Species: 8.18
Human Site: S455 Identified Species: 15
UniProt: Q2M1P5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2M1P5 NP_940927.2 1343 150587 S455 E G E R S A L S S A S G P D S
Chimpanzee Pan troglodytes XP_520097 1402 160381 L454 Q E V R K A V L T S F R G I G
Rhesus Macaque Macaca mulatta XP_001094468 1344 151200 S455 E G E R S A L S S A S G P D S
Dog Lupus familis XP_545852 1364 153156 A485 G P G G P K V A K G Q D E E G
Cat Felis silvestris
Mouse Mus musculus Q7M6Z4 1394 158937 L454 Q E V R K A V L T P L P G N Q
Rat Rattus norvegicus Q7M6Z5 1394 158861 L454 Q E V R K A V L T P L P G N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 H443 K L E Q L Q Q H A V C K L D L
Frog Xenopus laevis Q91784 1226 138905 H441 K M E E L K Q H A A C K V N L
Zebra Danio Brachydanio rerio Q58G59 1363 154819 T456 E E E R S G L T S A S G L D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 L82 A S A T Q T T L Y H E V V F P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46873 699 78760
Sea Urchin Strong. purpuratus P46872 699 78679
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 H354 L S T L D Y A H R A K N I R N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.2 97.4 86.3 N.A. 41 41.2 N.A. N.A. 24.5 24.2 58.1 N.A. 24.6 N.A. 24.3 23.6
Protein Similarity: 100 61 97.6 89.8 N.A. 60 60 N.A. N.A. 43.2 43.7 70.5 N.A. 38.4 N.A. 35.9 36.6
P-Site Identity: 100 13.3 100 0 N.A. 13.3 13.3 N.A. N.A. 13.3 13.3 73.3 N.A. 0 N.A. 0 0
P-Site Similarity: 100 40 100 20 N.A. 40 40 N.A. N.A. 33.3 33.3 80 N.A. 0 N.A. 0 0
Percent
Protein Identity: N.A. N.A. N.A. 25 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 39 8 8 16 39 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 8 0 31 0 % D
% Glu: 24 31 39 8 0 0 0 0 0 0 8 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % F
% Gly: 8 16 8 8 0 8 0 0 0 8 0 24 24 0 16 % G
% His: 0 0 0 0 0 0 0 24 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % I
% Lys: 16 0 0 0 24 16 0 0 8 0 8 16 0 0 0 % K
% Leu: 8 8 0 8 16 0 24 31 0 0 16 0 16 0 16 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 24 8 % N
% Pro: 0 8 0 0 8 0 0 0 0 16 0 16 16 0 8 % P
% Gln: 24 0 0 8 8 8 16 0 0 0 8 0 0 0 16 % Q
% Arg: 0 0 0 47 0 0 0 0 8 0 0 8 0 8 0 % R
% Ser: 0 16 0 0 24 0 0 16 24 8 24 0 0 0 24 % S
% Thr: 0 0 8 8 0 8 8 8 24 0 0 0 0 0 0 % T
% Val: 0 0 24 0 0 0 31 0 0 8 0 8 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _