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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF7 All Species: 13.03
Human Site: S617 Identified Species: 23.89
UniProt: Q2M1P5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2M1P5 NP_940927.2 1343 150587 S617 T E V N R L G S G S S A A S E
Chimpanzee Pan troglodytes XP_520097 1402 160381 S646 H C Q F S D N S D D E E S E G
Rhesus Macaque Macaca mulatta XP_001094468 1344 151200 S617 T E V N R L G S G S S A A S E
Dog Lupus familis XP_545852 1364 153156 S633 A E V D R P G S G S S A A S E
Cat Felis silvestris
Mouse Mus musculus Q7M6Z4 1394 158937 S646 H C Q F S D N S D D E D S E G
Rat Rattus norvegicus Q7M6Z5 1394 158861 R623 V F A G F R T R S Q M L M G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 L570 Y Q T N I K D L E L E V S N L
Frog Xenopus laevis Q91784 1226 138905 L567 Y L N N I K H L E S E V G V L
Zebra Danio Brachydanio rerio Q58G59 1363 154819 T616 E Q T Q W D G T H G N T H C E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 C192 P N L H A I N C K S V E D M I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46873 699 78760 R107 I E T I P A Q R G V I P R A F
Sea Urchin Strong. purpuratus P46872 699 78679 M107 G T G K T F T M E G V R S Q P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 T464 T E K N L S Q T C K V L A S T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.2 97.4 86.3 N.A. 41 41.2 N.A. N.A. 24.5 24.2 58.1 N.A. 24.6 N.A. 24.3 23.6
Protein Similarity: 100 61 97.6 89.8 N.A. 60 60 N.A. N.A. 43.2 43.7 70.5 N.A. 38.4 N.A. 35.9 36.6
P-Site Identity: 100 6.6 100 80 N.A. 6.6 0 N.A. N.A. 6.6 13.3 13.3 N.A. 6.6 N.A. 13.3 0
P-Site Similarity: 100 13.3 100 86.6 N.A. 13.3 0 N.A. N.A. 26.6 13.3 33.3 N.A. 26.6 N.A. 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. 25 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 8 8 0 0 0 0 0 24 31 8 0 % A
% Cys: 0 16 0 0 0 0 0 8 8 0 0 0 0 8 0 % C
% Asp: 0 0 0 8 0 24 8 0 16 16 0 8 8 0 0 % D
% Glu: 8 39 0 0 0 0 0 0 24 0 31 16 0 16 31 % E
% Phe: 0 8 0 16 8 8 0 0 0 0 0 0 0 0 8 % F
% Gly: 8 0 8 8 0 0 31 0 31 16 0 0 8 8 16 % G
% His: 16 0 0 8 0 0 8 0 8 0 0 0 8 0 8 % H
% Ile: 8 0 0 8 16 8 0 0 0 0 8 0 0 0 8 % I
% Lys: 0 0 8 8 0 16 0 0 8 8 0 0 0 0 0 % K
% Leu: 0 8 8 0 8 16 0 16 0 8 0 16 0 0 16 % L
% Met: 0 0 0 0 0 0 0 8 0 0 8 0 8 8 0 % M
% Asn: 0 8 8 39 0 0 24 0 0 0 8 0 0 8 0 % N
% Pro: 8 0 0 0 8 8 0 0 0 0 0 8 0 0 8 % P
% Gln: 0 16 16 8 0 0 16 0 0 8 0 0 0 8 0 % Q
% Arg: 0 0 0 0 24 8 0 16 0 0 0 8 8 0 0 % R
% Ser: 0 0 0 0 16 8 0 39 8 39 24 0 31 31 0 % S
% Thr: 24 8 24 0 8 0 16 16 0 0 0 8 0 0 8 % T
% Val: 8 0 24 0 0 0 0 0 0 8 24 16 0 8 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _