KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF7
All Species:
27.58
Human Site:
S742
Identified Species:
50.56
UniProt:
Q2M1P5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M1P5
NP_940927.2
1343
150587
S742
Q
A
L
N
R
Q
H
S
Q
R
I
R
E
L
E
Chimpanzee
Pan troglodytes
XP_520097
1402
160381
S758
K
S
V
S
K
Q
Y
S
L
K
V
T
K
L
E
Rhesus Macaque
Macaca mulatta
XP_001094468
1344
151200
S743
Q
A
L
N
R
Q
H
S
Q
R
I
R
E
L
E
Dog
Lupus familis
XP_545852
1364
153156
S763
Q
A
L
N
R
Q
H
S
Q
H
I
R
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7M6Z4
1394
158937
S758
K
S
V
S
R
Q
Y
S
L
K
V
T
K
L
E
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
S758
K
S
V
S
R
Q
Y
S
L
K
V
T
K
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
D675
R
Q
W
K
Q
Q
K
D
K
E
V
I
Q
L
K
Frog
Xenopus laevis
Q91784
1226
138905
T672
R
T
W
K
Q
Q
K
T
K
E
V
I
Q
L
K
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
S753
Q
A
M
N
R
Q
Y
S
R
K
I
S
E
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
P295
A
E
S
S
P
H
V
P
Y
R
D
S
K
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
F210
S
S
R
S
H
S
I
F
T
V
Y
V
E
G
M
Sea Urchin
Strong. purpuratus
P46872
699
78679
M210
R
S
V
G
A
T
N
M
N
E
S
S
S
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P82266
1056
119250
L567
L
S
Q
Q
N
V
H
L
Q
G
V
N
K
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.2
97.4
86.3
N.A.
41
41.2
N.A.
N.A.
24.5
24.2
58.1
N.A.
24.6
N.A.
24.3
23.6
Protein Similarity:
100
61
97.6
89.8
N.A.
60
60
N.A.
N.A.
43.2
43.7
70.5
N.A.
38.4
N.A.
35.9
36.6
P-Site Identity:
100
26.6
100
93.3
N.A.
33.3
33.3
N.A.
N.A.
13.3
13.3
66.6
N.A.
13.3
N.A.
6.6
0
P-Site Similarity:
100
86.6
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
53.3
60
93.3
N.A.
26.6
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
31
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
24
0
0
39
0
54
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
8
8
31
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
31
16
0
0
0
% I
% Lys:
24
0
0
16
8
0
16
0
16
31
0
0
39
0
16
% K
% Leu:
8
0
24
0
0
0
0
8
24
0
0
0
0
85
0
% L
% Met:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
31
8
0
8
0
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
31
8
8
8
16
70
0
0
31
0
0
0
16
0
0
% Q
% Arg:
24
0
8
0
47
0
0
0
8
24
0
24
0
8
0
% R
% Ser:
8
47
8
39
0
8
0
54
0
0
8
24
8
0
16
% S
% Thr:
0
8
0
0
0
8
0
8
8
0
0
24
0
0
8
% T
% Val:
0
0
31
0
0
8
8
0
0
8
47
8
0
0
0
% V
% Trp:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
31
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _