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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF7 All Species: 6.97
Human Site: T491 Identified Species: 12.78
UniProt: Q2M1P5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2M1P5 NP_940927.2 1343 150587 T491 E G A Q Q L L T L Q N Q V A R
Chimpanzee Pan troglodytes XP_520097 1402 160381 E505 Q K E L E V K E L K N Q V Q T
Rhesus Macaque Macaca mulatta XP_001094468 1344 151200 T491 E G A Q Q L R T L Q N Q V A R
Dog Lupus familis XP_545852 1364 153156 A516 E N R D F L A A L E D A M E Q
Cat Felis silvestris
Mouse Mus musculus Q7M6Z4 1394 158937 E505 Q K D L E L E E L R T Q V Q L
Rat Rattus norvegicus Q7M6Z5 1394 158861 Q511 E E L R R Q M Q L M A Q E S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 N471 E N V E V I R N L Q Q V L A Q
Frog Xenopus laevis Q91784 1226 138905 Q476 N L Q Q V I V Q L Q D E S S G
Zebra Danio Brachydanio rerio Q58G59 1363 154819 N484 K R R Q A V L N N Q D L V K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 T110 F A Y G Q T G T G K T F T M E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46873 699 78760 T24 R E K D L N T T L C V G M T P
Sea Urchin Strong. purpuratus P46872 699 78679 T25 R P L N S K E T G Q G F K S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 I382 I K D L Y G E I E R L K A E V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.2 97.4 86.3 N.A. 41 41.2 N.A. N.A. 24.5 24.2 58.1 N.A. 24.6 N.A. 24.3 23.6
Protein Similarity: 100 61 97.6 89.8 N.A. 60 60 N.A. N.A. 43.2 43.7 70.5 N.A. 38.4 N.A. 35.9 36.6
P-Site Identity: 100 26.6 93.3 20 N.A. 26.6 20 N.A. N.A. 26.6 20 26.6 N.A. 13.3 N.A. 13.3 13.3
P-Site Similarity: 100 53.3 93.3 46.6 N.A. 46.6 53.3 N.A. N.A. 53.3 53.3 46.6 N.A. 20 N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. 25 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 16 0 8 0 8 8 0 0 8 8 8 24 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 16 16 0 0 0 0 0 0 24 0 0 0 0 % D
% Glu: 39 16 8 8 16 0 24 16 8 8 0 8 8 16 16 % E
% Phe: 8 0 0 0 8 0 0 0 0 0 0 16 0 0 0 % F
% Gly: 0 16 0 8 0 8 8 0 16 0 8 8 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 16 0 8 0 0 0 0 0 0 0 % I
% Lys: 8 24 8 0 0 8 8 0 0 16 0 8 8 8 8 % K
% Leu: 0 8 16 24 8 31 16 0 70 0 8 8 8 0 8 % L
% Met: 0 0 0 0 0 0 8 0 0 8 0 0 16 8 0 % M
% Asn: 8 16 0 8 0 8 0 16 8 0 24 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 16 0 8 31 24 8 0 16 0 47 8 39 0 16 16 % Q
% Arg: 16 8 16 8 8 0 16 0 0 16 0 0 0 0 16 % R
% Ser: 0 0 0 0 8 0 0 0 0 0 0 0 8 24 0 % S
% Thr: 0 0 0 0 0 8 8 39 0 0 16 0 8 8 8 % T
% Val: 0 0 8 0 16 16 8 0 0 0 8 8 39 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _