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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF7 All Species: 21.21
Human Site: Y1186 Identified Species: 38.89
UniProt: Q2M1P5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2M1P5 NP_940927.2 1343 150587 Y1186 L A D S R R Q Y E A R I Q A L
Chimpanzee Pan troglodytes XP_520097 1402 160381 Y1199 I M E T F K T Y E D K I Q Q L
Rhesus Macaque Macaca mulatta XP_001094468 1344 151200 Y1187 L A D S R R Q Y E A R I Q A L
Dog Lupus familis XP_545852 1364 153156 Y1207 L A D S K R Q Y E T R I Q A L
Cat Felis silvestris
Mouse Mus musculus Q7M6Z4 1394 158937 Y1199 I I E T L K N Y E D K I Q Q L
Rat Rattus norvegicus Q7M6Z5 1394 158861 Y1199 I I E T L N K Y E D K I Q Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 G1091 C F C K G R C G N R Q C G C R
Frog Xenopus laevis Q91784 1226 138905 S1074 N W E P G N N S K Q S K K L T
Zebra Danio Brachydanio rerio Q58G59 1363 154819 Y1197 L A G R L R Q Y E G L I H N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 N661 F K S E N I V N Y E L E M P C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46873 699 78760 E576 E A V W N E D E S R W I L P E
Sea Urchin Strong. purpuratus P46872 699 78679 V576 M E A L L E N V R E L S R E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 D933 C Q A R C I E D K A Q E T F Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.2 97.4 86.3 N.A. 41 41.2 N.A. N.A. 24.5 24.2 58.1 N.A. 24.6 N.A. 24.3 23.6
Protein Similarity: 100 61 97.6 89.8 N.A. 60 60 N.A. N.A. 43.2 43.7 70.5 N.A. 38.4 N.A. 35.9 36.6
P-Site Identity: 100 33.3 100 86.6 N.A. 33.3 33.3 N.A. N.A. 6.6 0 53.3 N.A. 0 N.A. 13.3 6.6
P-Site Similarity: 100 66.6 100 93.3 N.A. 66.6 66.6 N.A. N.A. 13.3 20 53.3 N.A. 0 N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 25 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 39 16 0 0 0 0 0 0 24 0 0 0 24 0 % A
% Cys: 16 0 8 0 8 0 8 0 0 0 0 8 0 8 8 % C
% Asp: 0 0 24 0 0 0 8 8 0 24 0 0 0 0 0 % D
% Glu: 8 8 31 8 0 16 8 8 54 16 0 16 0 8 8 % E
% Phe: 8 8 0 0 8 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 8 0 16 0 0 8 0 8 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 24 16 0 0 0 16 0 0 0 0 0 62 0 0 0 % I
% Lys: 0 8 0 8 8 16 8 0 16 0 24 8 8 0 0 % K
% Leu: 31 0 0 8 31 0 0 0 0 0 24 0 8 8 62 % L
% Met: 8 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 16 16 24 8 8 0 0 0 0 8 0 % N
% Pro: 0 0 0 8 0 0 0 0 0 0 0 0 0 16 0 % P
% Gln: 0 8 0 0 0 0 31 0 0 8 16 0 47 24 8 % Q
% Arg: 0 0 0 16 16 39 0 0 8 16 24 0 8 0 8 % R
% Ser: 0 0 8 24 0 0 0 8 8 0 8 8 0 0 0 % S
% Thr: 0 0 0 24 0 0 8 0 0 8 0 0 8 0 8 % T
% Val: 0 0 8 0 0 0 8 8 0 0 0 0 0 0 0 % V
% Trp: 0 8 0 8 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 54 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _