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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISX
All Species:
2.73
Human Site:
S44
Identified Species:
6.67
UniProt:
Q2M1V0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M1V0
NP_001008494.1
245
27011
S44
L
K
R
P
A
R
R
S
D
M
D
R
P
E
G
Chimpanzee
Pan troglodytes
A2T711
184
20085
L16
P
A
T
E
G
G
G
L
G
P
G
E
E
A
P
Rhesus Macaque
Macaca mulatta
XP_001113063
245
26951
N44
L
K
R
P
A
R
R
N
D
V
D
R
P
E
G
Dog
Lupus familis
XP_853196
332
36290
S132
L
K
R
P
T
E
S
S
R
M
V
K
T
E
G
Cat
Felis silvestris
Mouse
Mus musculus
A1A546
240
27151
R40
L
K
K
P
T
E
R
R
S
L
P
R
P
Q
S
Rat
Rattus norvegicus
Q9JLT7
342
36319
A72
P
R
L
G
A
R
S
A
C
P
K
A
P
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PVX0
317
34038
G46
L
G
F
T
K
D
D
G
L
L
G
P
F
Q
P
Frog
Xenopus laevis
O42567
325
36295
E83
E
E
I
H
P
Q
Q
E
H
L
E
D
G
Q
T
Zebra Danio
Brachydanio rerio
O42356
330
36917
D50
L
G
F
N
K
D
Q
D
S
L
L
N
P
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119966
282
30412
R42
L
G
L
A
N
N
K
R
S
H
Q
E
M
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.5
93.4
52.7
N.A.
63.6
29.5
N.A.
N.A.
29.9
30.1
27.2
N.A.
N.A.
27.6
N.A.
N.A.
Protein Similarity:
100
39.1
95.9
56.9
N.A.
75.5
39.4
N.A.
N.A.
40.6
41.5
40.9
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
100
0
86.6
53.3
N.A.
40
26.6
N.A.
N.A.
6.6
0
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
0
100
60
N.A.
60
40
N.A.
N.A.
20
40
26.6
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
30
0
0
10
0
0
0
10
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
20
10
10
20
0
20
10
0
0
20
% D
% Glu:
10
10
0
10
0
20
0
10
0
0
10
20
10
40
0
% E
% Phe:
0
0
20
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
30
0
10
10
10
10
10
10
0
20
0
10
10
40
% G
% His:
0
0
0
10
0
0
0
0
10
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
40
10
0
20
0
10
0
0
0
10
10
0
0
0
% K
% Leu:
70
0
20
0
0
0
0
10
10
40
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
20
0
0
10
0
0
% M
% Asn:
0
0
0
10
10
10
0
10
0
0
0
10
0
0
0
% N
% Pro:
20
0
0
40
10
0
0
0
0
20
10
10
50
0
20
% P
% Gln:
0
0
0
0
0
10
20
0
0
0
10
0
0
30
0
% Q
% Arg:
0
10
30
0
0
30
30
20
10
0
0
30
0
0
0
% R
% Ser:
0
0
0
0
0
0
20
20
30
0
0
0
0
0
10
% S
% Thr:
0
0
10
10
20
0
0
0
0
0
0
0
10
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _