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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC27 All Species: 4.55
Human Site: S221 Identified Species: 14.29
UniProt: Q2M243 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2M243 NP_689705.2 656 75354 S221 S S S V A S Q S C L R K R M P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001084364 594 68682 M221 G K G Q E A S M S P G R R E R
Dog Lupus familis XP_546741 909 101351 S457 S S P V L A Q S H P N K R L P
Cat Felis silvestris
Mouse Mus musculus Q3V036 639 73632 G239 Q L K N L L R G K G T E T S S
Rat Rattus norvegicus XP_001053589 621 71758 E224 E I L M L Q K E K E A L R K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519238 324 36511
Chicken Gallus gallus XP_417544 494 54679 P125 D L Q S G H G P A G E Q D G K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001073550 408 47532 S39 R T A R S S A S S D T P S P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 82.7 42.3 N.A. 51 49.2 N.A. 22.5 30.4 N.A. 21 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 85.5 53 N.A. 66.6 64.7 N.A. 32.7 45.7 N.A. 36.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 6.6 53.3 N.A. 0 6.6 N.A. 0 0 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 20 66.6 N.A. 13.3 20 N.A. 0 6.6 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 13 25 13 0 13 0 13 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % C
% Asp: 13 0 0 0 0 0 0 0 0 13 0 0 13 0 0 % D
% Glu: 13 0 0 0 13 0 0 13 0 13 13 13 0 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 0 13 0 13 0 13 13 0 25 13 0 0 13 13 % G
% His: 0 0 0 0 0 13 0 0 13 0 0 0 0 0 0 % H
% Ile: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 13 13 0 0 0 13 0 25 0 0 25 0 13 13 % K
% Leu: 0 25 13 0 38 13 0 0 0 13 0 13 0 13 0 % L
% Met: 0 0 0 13 0 0 0 13 0 0 0 0 0 13 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 13 0 0 0 0 % N
% Pro: 0 0 13 0 0 0 0 13 0 25 0 13 0 13 25 % P
% Gln: 13 0 13 13 0 13 25 0 0 0 0 13 0 0 13 % Q
% Arg: 13 0 0 13 0 0 13 0 0 0 13 13 50 0 13 % R
% Ser: 25 25 13 13 13 25 13 38 25 0 0 0 13 13 13 % S
% Thr: 0 13 0 0 0 0 0 0 0 0 25 0 13 0 0 % T
% Val: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _