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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AAK1
All Species:
11.52
Human Site:
S406
Identified Species:
36.19
UniProt:
Q2M2I8
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M2I8
NP_055726.3
863
93578
S406
P
P
Q
A
A
G
S
S
N
Q
P
G
L
L
A
Chimpanzee
Pan troglodytes
XP_001138187
865
93810
S406
P
P
Q
A
A
G
S
S
N
Q
P
G
L
L
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531855
473
51892
M69
L
V
R
T
S
N
G
M
K
C
A
L
K
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHJ0
959
103328
S406
L
P
Q
A
A
G
P
S
N
Q
P
G
L
L
P
Rat
Rattus norvegicus
P0C1X8
962
103742
S405
L
P
Q
A
T
G
P
S
N
Q
P
S
L
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417663
953
102927
A406
A
I
Q
P
Q
G
P
A
A
L
G
S
G
Q
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625109
598
65629
V194
S
V
H
G
A
A
I
V
E
E
E
I
K
K
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40494
810
91014
H390
A
G
L
Q
V
G
S
H
S
N
L
T
S
P
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
53.7
N.A.
80.7
79.9
N.A.
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
54.4
N.A.
83.1
82.7
N.A.
N.A.
77.9
N.A.
N.A.
N.A.
N.A.
50
N.A.
N.A.
P-Site Identity:
100
100
N.A.
0
N.A.
80
73.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
13.3
N.A.
80
73.3
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
50
50
13
0
13
13
0
13
0
0
0
38
% A
% Cys:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
13
13
13
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
13
0
75
13
0
0
0
13
38
13
0
0
% G
% His:
0
0
13
0
0
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
0
13
0
0
0
0
13
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
13
0
0
0
25
13
0
% K
% Leu:
38
0
13
0
0
0
0
0
0
13
13
13
50
50
13
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
13
% M
% Asn:
0
0
0
0
0
13
0
0
50
13
0
0
0
0
0
% N
% Pro:
25
50
0
13
0
0
38
0
0
0
50
0
0
13
25
% P
% Gln:
0
0
63
13
13
0
0
0
0
50
0
0
0
13
0
% Q
% Arg:
0
0
13
0
0
0
0
0
0
0
0
0
0
13
0
% R
% Ser:
13
0
0
0
13
0
38
50
13
0
0
25
13
0
0
% S
% Thr:
0
0
0
13
13
0
0
0
0
0
0
13
0
0
0
% T
% Val:
0
25
0
0
13
0
0
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _