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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AAK1 All Species: 18.83
Human Site: S7 Identified Species: 59.18
UniProt: Q2M2I8 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2M2I8 NP_055726.3 863 93578 S7 _ M K K F F D S R R E Q G G S
Chimpanzee Pan troglodytes XP_001138187 865 93810 S7 _ M K K F F D S R R E Q G G S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531855 473 51892
Cat Felis silvestris
Mouse Mus musculus Q3UHJ0 959 103328 S7 _ M K K F F D S R R E Q G S S
Rat Rattus norvegicus P0C1X8 962 103742 S7 _ M K K F F D S R R E Q G S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417663 953 102927 S7 _ M K K F F D S R R E Q G G S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625109 598 65629
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40494 810 91014 S7 _ M N T P Q I S L Y E P G T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 53.7 N.A. 80.7 79.9 N.A. N.A. 71.4 N.A. N.A. N.A. N.A. 36.7 N.A. N.A.
Protein Similarity: 100 99.6 N.A. 54.4 N.A. 83.1 82.7 N.A. N.A. 77.9 N.A. N.A. N.A. N.A. 50 N.A. N.A.
P-Site Identity: 100 100 N.A. 0 N.A. 92.8 92.8 N.A. N.A. 100 N.A. N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 N.A. 0 N.A. 92.8 92.8 N.A. N.A. 100 N.A. N.A. N.A. N.A. 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 28.5 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 28.5 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 63 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 % E
% Phe: 0 0 0 0 63 63 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 75 38 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 13 % I
% Lys: 0 0 63 63 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % L
% Met: 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 13 0 0 0 0 0 0 13 0 0 0 % P
% Gln: 0 0 0 0 0 13 0 0 0 0 0 63 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 63 63 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 75 0 0 0 0 0 25 63 % S
% Thr: 0 0 0 13 0 0 0 0 0 0 0 0 0 13 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % Y
% Spaces: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _