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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPHKAP All Species: 18.79
Human Site: S1534 Identified Species: 51.67
UniProt: Q2M3C7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2M3C7 NP_001136116.1 1700 186456 S1534 E D N P D D T S S F L Q L S E
Chimpanzee Pan troglodytes XP_001137841 1700 186330 S1534 E D N P D D T S S F L Q L S E
Rhesus Macaque Macaca mulatta XP_001111587 1700 186695 S1534 E D N P D D T S S F L Q L S E
Dog Lupus familis XP_852306 1660 181751 E1504 N L S G S S G E S T D S W S Q
Cat Felis silvestris
Mouse Mus musculus Q6NSW3 1687 185076 S1521 E D I P D D T S S F L Q L S E
Rat Rattus norvegicus P0C6C0 1683 184433 S1517 E D N P D D T S S F L Q L S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505678 1397 151200 S1244 I H E T W A N S I E A L M R K
Chicken Gallus gallus NP_001171003 1656 183394 L1495 A E E F P T H L S S S E E S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LV19 1596 174544 G1443 N S S T S S L G L A D L E G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95 73.8 N.A. 72.2 72.1 N.A. 39.6 54.5 N.A. 39.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 96.5 81 N.A. 81.1 81.7 N.A. 51.1 69.1 N.A. 56.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 93.3 100 N.A. 6.6 13.3 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 93.3 100 N.A. 20 26.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 12 0 0 0 12 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 56 0 0 56 56 0 0 0 0 23 0 0 0 0 % D
% Glu: 56 12 23 0 0 0 0 12 0 12 0 12 23 0 56 % E
% Phe: 0 0 0 12 0 0 0 0 0 56 0 0 0 0 12 % F
% Gly: 0 0 0 12 0 0 12 12 0 0 0 0 0 12 0 % G
% His: 0 12 0 0 0 0 12 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 12 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % K
% Leu: 0 12 0 0 0 0 12 12 12 0 56 23 56 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % M
% Asn: 23 0 45 0 0 0 12 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 56 12 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 56 0 0 12 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % R
% Ser: 0 12 23 0 23 23 0 67 78 12 12 12 0 78 0 % S
% Thr: 0 0 0 23 0 12 56 0 0 12 0 0 0 0 12 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 12 0 0 0 0 0 0 0 12 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _