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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB5
All Species:
13.64
Human Site:
S538
Identified Species:
30
UniProt:
Q2M3G0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M3G0
NP_848654.3
812
89831
S538
P
E
Y
S
K
A
K
S
G
A
A
H
L
F
A
Chimpanzee
Pan troglodytes
XP_001152831
1186
130928
S912
P
E
Y
S
K
A
K
S
G
A
A
H
L
F
A
Rhesus Macaque
Macaca mulatta
XP_001102010
1140
125473
S866
P
E
Y
S
K
A
K
S
G
A
A
H
L
F
A
Dog
Lupus familis
XP_539461
1269
140189
S995
P
E
Y
S
R
A
K
S
G
A
A
H
L
F
A
Cat
Felis silvestris
Mouse
Mus musculus
P21440
1276
140314
L999
P
D
Y
A
K
A
K
L
S
A
A
Y
L
F
S
Rat
Rattus norvegicus
Q08201
1278
140637
L1001
P
D
Y
A
K
A
K
L
S
A
A
Y
L
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990225
1288
141899
I1011
P
D
Y
A
K
A
K
I
S
A
A
H
L
F
V
Frog
Xenopus laevis
NP_001081394
1287
141487
M1011
A
P
D
Y
T
K
A
M
I
S
A
A
H
I
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00748
1302
143766
I1023
P
A
F
S
A
A
L
I
A
G
H
R
L
F
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34712
1321
145045
A1044
Y
F
P
E
Y
A
K
A
T
F
A
G
G
I
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FWX7
1278
137648
V1000
P
D
S
S
K
A
K
V
A
A
A
S
I
F
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
67.9
54.4
N.A.
37.8
37.4
N.A.
N.A.
36.9
36.1
N.A.
N.A.
26.8
N.A.
26.7
N.A.
Protein Similarity:
100
67.8
69.5
58.7
N.A.
50
49.7
N.A.
N.A.
48.9
48.7
N.A.
N.A.
40.8
N.A.
41.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
60
60
N.A.
N.A.
66.6
6.6
N.A.
N.A.
33.3
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
80
13.3
N.A.
N.A.
40
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
28
10
91
10
10
19
73
91
10
0
0
46
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
37
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
37
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
10
0
0
0
0
0
0
10
0
0
0
82
10
% F
% Gly:
0
0
0
0
0
0
0
0
37
10
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
46
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
19
10
0
0
0
10
19
10
% I
% Lys:
0
0
0
0
64
10
82
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
19
0
0
0
0
73
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
82
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
10
55
0
0
0
37
28
10
0
10
0
0
19
% S
% Thr:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
64
10
10
0
0
0
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _