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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB5
All Species:
26.97
Human Site:
S672
Identified Species:
59.33
UniProt:
Q2M3G0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M3G0
NP_848654.3
812
89831
S672
N
I
A
Y
G
D
N
S
R
V
V
P
L
D
E
Chimpanzee
Pan troglodytes
XP_001152831
1186
130928
S1046
N
I
A
Y
G
D
N
S
R
V
V
P
L
D
E
Rhesus Macaque
Macaca mulatta
XP_001102010
1140
125473
S1000
N
I
A
Y
G
D
N
S
R
V
V
S
L
D
E
Dog
Lupus familis
XP_539461
1269
140189
S1129
N
I
A
Y
G
D
N
S
R
V
V
S
L
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P21440
1276
140314
S1133
N
I
A
Y
G
D
N
S
R
V
V
P
H
D
E
Rat
Rattus norvegicus
Q08201
1278
140637
S1135
N
I
A
Y
G
D
N
S
R
V
V
S
Q
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990225
1288
141899
S1145
N
I
A
Y
G
D
N
S
R
E
V
S
H
E
E
Frog
Xenopus laevis
NP_001081394
1287
141487
N1146
N
I
A
Y
G
D
N
N
R
K
V
T
Q
E
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00748
1302
143766
R1162
N
I
A
Y
G
D
N
R
R
S
V
S
M
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34712
1321
145045
P1179
N
I
I
Y
G
L
D
P
S
S
V
T
M
A
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FWX7
1278
137648
S1134
N
I
A
Y
G
K
G
S
E
E
A
A
T
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
67.9
54.4
N.A.
37.8
37.4
N.A.
N.A.
36.9
36.1
N.A.
N.A.
26.8
N.A.
26.7
N.A.
Protein Similarity:
100
67.8
69.5
58.7
N.A.
50
49.7
N.A.
N.A.
48.9
48.7
N.A.
N.A.
40.8
N.A.
41.1
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
86.6
N.A.
N.A.
73.3
66.6
N.A.
N.A.
66.6
N.A.
33.3
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
86.6
N.A.
N.A.
80
80
N.A.
N.A.
73.3
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
91
0
0
0
0
0
0
0
10
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
82
10
0
0
0
0
0
0
55
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
19
0
0
0
28
82
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
100
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% H
% Ile:
0
100
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
37
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% M
% Asn:
100
0
0
0
0
0
82
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
28
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
10
% Q
% Arg:
0
0
0
0
0
0
0
10
82
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
73
10
19
0
46
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
19
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
55
91
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _