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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB5
All Species:
13.33
Human Site:
Y15
Identified Species:
29.33
UniProt:
Q2M3G0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M3G0
NP_848654.3
812
89831
Y15
R
A
L
N
V
R
H
Y
R
D
H
I
G
V
V
Chimpanzee
Pan troglodytes
XP_001152831
1186
130928
Y389
R
A
L
N
V
R
H
Y
R
D
H
I
G
V
V
Rhesus Macaque
Macaca mulatta
XP_001102010
1140
125473
Y343
R
A
L
N
V
R
H
Y
R
E
H
I
G
V
V
Dog
Lupus familis
XP_539461
1269
140189
Y460
R
T
L
N
V
Q
H
Y
R
E
H
I
G
V
V
Cat
Felis silvestris
Mouse
Mus musculus
P21440
1276
140314
L465
R
N
F
N
V
R
C
L
R
E
I
I
G
V
V
Rat
Rattus norvegicus
Q08201
1278
140637
L465
R
N
F
N
V
R
C
L
R
E
F
I
G
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990225
1288
141899
L474
K
S
L
N
V
R
Y
L
R
E
I
I
G
V
V
Frog
Xenopus laevis
NP_001081394
1287
141487
L476
R
S
L
N
I
R
Y
L
R
E
I
I
G
V
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00748
1302
143766
L479
R
K
Y
N
I
Q
W
L
R
S
N
I
A
V
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34712
1321
145045
L490
R
D
I
N
L
E
F
L
R
K
N
V
A
V
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FWX7
1278
137648
I455
K
E
F
Q
L
K
W
I
R
S
K
I
G
L
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
67.9
54.4
N.A.
37.8
37.4
N.A.
N.A.
36.9
36.1
N.A.
N.A.
26.8
N.A.
26.7
N.A.
Protein Similarity:
100
67.8
69.5
58.7
N.A.
50
49.7
N.A.
N.A.
48.9
48.7
N.A.
N.A.
40.8
N.A.
41.1
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
60
60
N.A.
N.A.
60
60
N.A.
N.A.
40
N.A.
33.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
66.6
66.6
N.A.
N.A.
86.6
86.6
N.A.
N.A.
60
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
28
0
0
0
0
0
0
0
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
19
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
10
0
0
0
55
0
0
0
0
0
% E
% Phe:
0
0
28
0
0
0
10
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% G
% His:
0
0
0
0
0
0
37
0
0
0
37
0
0
0
0
% H
% Ile:
0
0
10
0
19
0
0
10
0
0
28
91
0
0
0
% I
% Lys:
19
10
0
0
0
10
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
0
55
0
19
0
0
55
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
91
0
0
0
0
0
0
19
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
19
0
0
0
0
0
0
0
0
0
% Q
% Arg:
82
0
0
0
0
64
0
0
100
0
0
0
0
0
0
% R
% Ser:
0
19
0
0
0
0
0
0
0
19
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
64
0
0
0
0
0
0
10
0
91
100
% V
% Trp:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
19
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _