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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB5
All Species:
34.24
Human Site:
Y39
Identified Species:
75.33
UniProt:
Q2M3G0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M3G0
NP_848654.3
812
89831
Y39
T
I
S
N
N
I
K
Y
G
R
D
D
V
T
D
Chimpanzee
Pan troglodytes
XP_001152831
1186
130928
Y413
T
I
S
N
N
I
K
Y
G
R
D
D
V
T
D
Rhesus Macaque
Macaca mulatta
XP_001102010
1140
125473
Y367
T
I
S
N
N
I
K
Y
G
R
D
D
V
T
D
Dog
Lupus familis
XP_539461
1269
140189
Y484
T
I
H
N
N
I
K
Y
G
R
D
G
V
T
D
Cat
Felis silvestris
Mouse
Mus musculus
P21440
1276
140314
Y489
T
I
A
E
N
I
R
Y
G
R
G
N
V
T
M
Rat
Rattus norvegicus
Q08201
1278
140637
Y489
T
I
A
E
N
I
R
Y
G
R
G
N
V
T
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990225
1288
141899
Y498
T
I
A
E
N
I
R
Y
G
R
E
D
V
T
M
Frog
Xenopus laevis
NP_001081394
1287
141487
Y500
T
I
A
D
N
I
R
Y
G
R
E
D
V
T
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00748
1302
143766
Y503
T
I
A
Q
N
I
S
Y
G
K
P
G
A
T
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34712
1321
145045
L514
T
I
E
E
N
I
S
L
G
K
E
G
I
T
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FWX7
1278
137648
Y479
S
I
M
E
N
I
A
Y
G
K
E
N
A
T
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
67.9
54.4
N.A.
37.8
37.4
N.A.
N.A.
36.9
36.1
N.A.
N.A.
26.8
N.A.
26.7
N.A.
Protein Similarity:
100
67.8
69.5
58.7
N.A.
50
49.7
N.A.
N.A.
48.9
48.7
N.A.
N.A.
40.8
N.A.
41.1
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
60
60
N.A.
N.A.
66.6
66.6
N.A.
N.A.
46.6
N.A.
40
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
N.A.
86.6
93.3
N.A.
N.A.
60
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
46
0
0
0
10
0
0
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
37
46
0
0
37
% D
% Glu:
0
0
10
46
0
0
0
0
0
0
37
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
100
0
19
28
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
100
0
0
0
100
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
37
0
0
28
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
28
% M
% Asn:
0
0
0
37
100
0
0
0
0
0
0
28
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
37
0
0
73
0
0
0
0
10
% R
% Ser:
10
0
28
0
0
0
19
0
0
0
0
0
0
0
0
% S
% Thr:
91
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
73
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _