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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHROOM1
All Species:
11.82
Human Site:
Y422
Identified Species:
28.89
UniProt:
Q2M3G4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M3G4
NP_597713.1
852
90786
Y422
V
H
A
S
D
Q
P
Y
G
T
G
L
G
Q
R
Chimpanzee
Pan troglodytes
XP_527007
1270
134830
Y840
V
H
A
S
D
Q
P
Y
G
T
G
L
G
Q
R
Rhesus Macaque
Macaca mulatta
XP_001100079
902
95451
Y472
V
H
A
S
D
Q
Q
Y
G
T
G
L
G
Q
R
Dog
Lupus familis
XP_538623
653
70619
L333
P
S
P
R
L
E
E
L
V
Q
E
L
A
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5SX79
823
89933
A416
A
G
Q
I
A
V
S
A
E
R
P
L
H
E
T
Rat
Rattus norvegicus
XP_001073965
858
92755
S433
T
S
T
S
D
R
P
S
E
N
G
L
S
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514972
1675
186527
D1134
G
N
K
Y
R
R
P
D
V
S
T
P
S
S
G
Chicken
Gallus gallus
XP_414650
769
84718
T412
S
Q
T
G
N
A
L
T
T
C
P
E
L
Q
P
Frog
Xenopus laevis
Q01613
1420
159450
F1012
G
E
A
T
A
L
S
F
T
F
L
P
E
Q
D
Zebra Danio
Brachydanio rerio
XP_687790
1216
137177
P777
V
E
S
L
L
D
Q
P
E
Q
P
K
L
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66
87.4
51.6
N.A.
59.2
61.3
N.A.
20.8
20.1
20.2
20.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
66.4
89.1
57.1
N.A.
66.5
68.4
N.A.
31.1
35.6
32.5
34
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
33.3
N.A.
6.6
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
13.3
53.3
N.A.
26.6
13.3
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
40
0
20
10
0
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
40
10
0
10
0
0
0
0
0
0
10
% D
% Glu:
0
20
0
0
0
10
10
0
30
0
10
10
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% F
% Gly:
20
10
0
10
0
0
0
0
30
0
40
0
30
0
10
% G
% His:
0
30
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
10
0
10
10
% K
% Leu:
0
0
0
10
20
10
10
10
0
0
10
60
20
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
10
0
10
0
0
0
40
10
0
0
30
20
0
10
10
% P
% Gln:
0
10
10
0
0
30
20
0
0
20
0
0
0
50
0
% Q
% Arg:
0
0
0
10
10
20
0
0
0
10
0
0
0
10
40
% R
% Ser:
10
20
10
40
0
0
20
10
0
10
0
0
20
10
0
% S
% Thr:
10
0
20
10
0
0
0
10
20
30
10
0
0
0
10
% T
% Val:
40
0
0
0
0
10
0
0
20
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _