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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS21
All Species:
25.15
Human Site:
Y116
Identified Species:
55.33
UniProt:
Q2M5E4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M5E4
NP_001034241.1
152
17671
Y116
D
E
A
Q
K
L
I
Y
C
L
M
A
K
D
S
Chimpanzee
Pan troglodytes
XP_001166182
152
17683
Y116
D
E
A
Q
K
L
I
Y
C
L
M
A
K
D
S
Rhesus Macaque
Macaca mulatta
XP_001113001
152
17744
Y116
D
E
A
Q
K
L
I
Y
C
L
M
A
K
D
S
Dog
Lupus familis
XP_849754
222
25131
V177
D
Q
K
K
N
I
P
V
T
A
E
E
A
K
I
Cat
Felis silvestris
Mouse
Mus musculus
O08849
211
24275
Y178
T
T
A
Q
K
R
V
Y
S
L
M
E
N
N
S
Rat
Rattus norvegicus
Q9JHX0
211
24304
Y178
T
T
A
Q
K
R
V
Y
S
L
M
E
N
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516424
168
19575
Y132
D
D
A
Q
R
L
I
Y
S
L
M
A
K
D
S
Chicken
Gallus gallus
Q7SZC6
208
23504
F157
D
E
A
Q
R
K
I
F
T
L
M
E
K
D
S
Frog
Xenopus laevis
A1A643
201
23280
F170
N
G
A
Q
K
M
I
F
I
L
M
E
R
D
S
Zebra Danio
Brachydanio rerio
Q6DGI0
174
20503
Y141
N
E
V
Q
A
K
V
Y
S
L
M
E
K
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49808
169
19576
Y138
D
E
A
Q
N
Q
I
Y
T
L
M
Q
R
D
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
95.3
56.7
N.A.
39.3
39.3
N.A.
73.8
37
37.8
43
N.A.
N.A.
N.A.
37.2
N.A.
Protein Similarity:
100
99.3
96.7
59
N.A.
52.1
52.1
N.A.
82.7
52.8
55.2
60.3
N.A.
N.A.
N.A.
59.1
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
46.6
46.6
N.A.
80
66.6
53.3
53.3
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
60
60
N.A.
93.3
80
80
66.6
N.A.
N.A.
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
82
0
10
0
0
0
0
10
0
37
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
28
0
0
0
0
0
0
% C
% Asp:
64
10
0
0
0
0
0
0
0
0
0
0
0
73
0
% D
% Glu:
0
55
0
0
0
0
0
0
0
0
10
55
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
64
0
10
0
0
0
0
0
10
% I
% Lys:
0
0
10
10
55
19
0
0
0
0
0
0
55
10
0
% K
% Leu:
0
0
0
0
0
37
0
0
0
91
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
91
0
0
0
0
% M
% Asn:
19
0
0
0
19
0
0
0
0
0
0
0
19
19
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
91
0
10
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
19
19
0
0
0
0
0
0
19
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
37
0
0
0
0
0
91
% S
% Thr:
19
19
0
0
0
0
0
0
28
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
28
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _