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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPRED3 All Species: 16.97
Human Site: S126 Identified Species: 37.33
UniProt: Q2MJR0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2MJR0 NP_001035987.1 410 42670 S126 T P S S S S S S S S P S Q D T
Chimpanzee Pan troglodytes XP_001166773 410 42535 S126 T P S S S S S S S S P S Q D T
Rhesus Macaque Macaca mulatta XP_001107519 412 42812 S126 T P S S S S S S S S S S P S Q
Dog Lupus familis XP_855400 429 44705 S145 T P S S S S S S S S P S Q D T
Cat Felis silvestris
Mouse Mus musculus Q6P6N5 408 42776 S126 T P S S S S S S S S P S Q D T
Rat Rattus norvegicus Q3C2P8 410 46787 N135 T S S S T I H N E A E L G D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513496 539 60559 N253 T S S S T I H N E A E L G D D
Chicken Gallus gallus XP_419341 612 68767 N335 T S S S T L H N E A E V G D D
Frog Xenopus laevis NP_001121277 405 45787 E133 A S C H G E S E A S E D G P Q
Zebra Danio Brachydanio rerio Q6NYK3 413 46811 N135 T S S S T L Q N E A E L G D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395474 376 41869 L133 N S T Y D N S L D A G D E D V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 98.7 92.3 N.A. 94.3 40 N.A. 29.1 22.8 39.5 37.7 N.A. N.A. 35.8 N.A. N.A.
Protein Similarity: 100 97.8 99.5 93.9 N.A. 95.6 54.1 N.A. 39.5 36.5 52.9 51.5 N.A. N.A. 47 N.A. N.A.
P-Site Identity: 100 100 73.3 100 N.A. 100 26.6 N.A. 26.6 26.6 13.3 26.6 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 100 73.3 100 N.A. 100 46.6 N.A. 46.6 46.6 20 46.6 N.A. N.A. 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 10 46 0 0 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 10 0 0 19 0 82 37 % D
% Glu: 0 0 0 0 0 10 0 10 37 0 46 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 0 0 10 0 46 0 0 % G
% His: 0 0 0 10 0 0 28 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 19 0 10 0 0 0 28 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 10 0 37 0 0 0 0 0 0 0 % N
% Pro: 0 46 0 0 0 0 0 0 0 0 37 0 10 10 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 37 0 19 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 55 82 82 46 46 64 46 46 55 10 46 0 10 0 % S
% Thr: 82 0 10 0 37 0 0 0 0 0 0 0 0 0 37 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _