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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSPO1 All Species: 18.79
Human Site: S134 Identified Species: 59.05
UniProt: Q2MKA7 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2MKA7 NP_001033722.1 263 28959 S134 P A C P E G S S A A N G T M E
Chimpanzee Pan troglodytes XP_001169684 263 28971 S134 P A C P E G S S A A N G T M E
Rhesus Macaque Macaca mulatta XP_001112136 262 28776 S134 P A C P E G S S A A N G T M E
Dog Lupus familis XP_533492 295 32962 E154 D N C P E G L E A N N H T M E
Cat Felis silvestris
Mouse Mus musculus Q9Z132 265 29313 T134 P A C P E G S T A A N S T M E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511749 265 29412 S134 P D C P S G Y S A A N G T M E
Chicken Gallus gallus
Frog Xenopus laevis Q5UE90 243 27861 G131 C F E E C P E G F A P L D D T
Zebra Danio Brachydanio rerio Q6DHR0 261 29032 T135 S S C P E G F T V N G T M E C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 96.9 41 N.A. 87.9 N.A. N.A. 76.2 N.A. 38.7 53.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 98 55.5 N.A. 91.6 N.A. N.A. 84.1 N.A. 55.5 69.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 60 N.A. 86.6 N.A. N.A. 80 N.A. 6.6 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 60 N.A. 93.3 N.A. N.A. 80 N.A. 6.6 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 0 0 0 0 0 0 75 75 0 0 0 0 0 % A
% Cys: 13 0 88 0 13 0 0 0 0 0 0 0 0 0 13 % C
% Asp: 13 13 0 0 0 0 0 0 0 0 0 0 13 13 0 % D
% Glu: 0 0 13 13 75 0 13 13 0 0 0 0 0 13 75 % E
% Phe: 0 13 0 0 0 0 13 0 13 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 88 0 13 0 0 13 50 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 13 0 0 0 0 13 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 13 75 0 % M
% Asn: 0 13 0 0 0 0 0 0 0 25 75 0 0 0 0 % N
% Pro: 63 0 0 88 0 13 0 0 0 0 13 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 13 0 0 13 0 50 50 0 0 0 13 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 25 0 0 0 13 75 0 13 % T
% Val: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _