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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSPO1
All Species:
21.21
Human Site:
S172
Identified Species:
66.67
UniProt:
Q2MKA7
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2MKA7
NP_001033722.1
263
28959
S172
L
C
G
F
R
R
G
S
E
E
R
T
R
R
V
Chimpanzee
Pan troglodytes
XP_001169684
263
28971
S172
L
C
G
F
R
R
G
S
E
E
R
T
R
R
V
Rhesus Macaque
Macaca mulatta
XP_001112136
262
28776
S172
L
C
G
F
R
R
G
S
E
E
R
T
R
R
V
Dog
Lupus familis
XP_533492
295
32962
T192
T
C
G
F
K
R
G
T
E
T
R
V
R
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z132
265
29313
S172
L
C
G
F
R
K
G
S
E
E
R
T
R
R
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511749
265
29412
T172
L
C
G
F
R
K
G
T
E
E
R
A
R
R
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5UE90
243
27861
L169
T
C
G
F
K
W
G
L
E
T
R
T
R
Q
I
Zebra Danio
Brachydanio rerio
Q6DHR0
261
29032
R173
F
K
K
G
N
Q
T
R
T
R
E
P
L
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
96.9
41
N.A.
87.9
N.A.
N.A.
76.2
N.A.
38.7
53.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98
55.5
N.A.
91.6
N.A.
N.A.
84.1
N.A.
55.5
69.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
53.3
N.A.
93.3
N.A.
N.A.
80
N.A.
53.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
100
N.A.
N.A.
93.3
N.A.
73.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% A
% Cys:
0
88
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
88
63
13
0
0
13
0
% E
% Phe:
13
0
0
88
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
88
13
0
0
88
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% I
% Lys:
0
13
13
0
25
25
0
0
0
0
0
0
0
0
0
% K
% Leu:
63
0
0
0
0
0
0
13
0
0
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% P
% Gln:
0
0
0
0
0
13
0
0
0
0
0
0
0
25
0
% Q
% Arg:
0
0
0
0
63
50
0
13
0
13
88
0
88
63
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
25
0
0
0
0
0
13
25
13
25
0
63
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
75
% V
% Trp:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _