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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC6L
All Species:
6.97
Human Site:
S1041
Identified Species:
21.9
UniProt:
Q2NKX8
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2NKX8
NP_060139.2
1250
141103
S1041
D
D
S
F
K
D
T
S
S
I
N
P
F
N
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092609
1252
141491
S1045
D
D
S
F
K
D
T
S
S
T
N
P
F
N
T
Dog
Lupus familis
XP_549075
1268
143171
T1060
E
D
K
T
F
Q
D
T
P
G
T
N
L
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHK9
1240
138836
S1035
E
E
D
A
F
K
G
S
H
T
N
S
I
N
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505482
1393
155753
M1038
G
E
E
P
E
A
L
M
S
P
L
R
N
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BGR3
1451
163208
N1192
N
E
S
D
E
E
S
N
E
D
K
T
K
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41877
1009
116656
R819
R
G
N
E
K
Y
G
R
E
D
L
E
S
I
A
Sea Urchin
Strong. purpuratus
XP_781405
563
63991
I373
L
T
R
K
N
D
L
I
V
W
L
S
L
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.5
78.8
N.A.
73.4
N.A.
N.A.
49.9
N.A.
N.A.
44.4
N.A.
N.A.
N.A.
24.7
22.9
Protein Similarity:
100
N.A.
98.4
85.8
N.A.
82.3
N.A.
N.A.
63.8
N.A.
N.A.
60
N.A.
N.A.
N.A.
42.7
33.2
P-Site Identity:
100
N.A.
93.3
13.3
N.A.
20
N.A.
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
N.A.
93.3
26.6
N.A.
33.3
N.A.
N.A.
26.6
N.A.
N.A.
60
N.A.
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
13
0
0
0
0
0
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
38
13
13
0
38
13
0
0
25
0
0
0
0
0
% D
% Glu:
25
38
13
13
25
13
0
0
25
0
0
13
0
0
13
% E
% Phe:
0
0
0
25
25
0
0
0
0
0
0
0
25
13
0
% F
% Gly:
13
13
0
0
0
0
25
0
0
13
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
13
0
0
13
13
13
% I
% Lys:
0
0
13
13
38
13
0
0
0
0
13
0
13
0
0
% K
% Leu:
13
0
0
0
0
0
25
0
0
0
38
0
25
0
0
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
13
0
13
0
13
0
0
13
0
0
38
13
13
38
0
% N
% Pro:
0
0
0
13
0
0
0
0
13
13
0
25
0
0
0
% P
% Gln:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
13
0
0
0
0
13
0
0
0
13
0
0
0
% R
% Ser:
0
0
38
0
0
0
13
38
38
0
0
25
13
25
13
% S
% Thr:
0
13
0
13
0
0
25
13
0
25
13
13
0
13
38
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _