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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC6L
All Species:
14.85
Human Site:
S1158
Identified Species:
46.67
UniProt:
Q2NKX8
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2NKX8
NP_060139.2
1250
141103
S1158
L
S
S
E
N
K
S
S
W
L
M
T
S
K
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092609
1252
141491
S1162
L
S
S
E
N
K
S
S
W
L
T
T
S
K
P
Dog
Lupus familis
XP_549075
1268
143171
S1176
L
P
S
E
H
K
S
S
W
L
T
T
R
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHK9
1240
138836
S1149
L
A
S
G
N
K
S
S
N
L
T
M
S
E
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505482
1393
155753
E1161
V
E
E
D
D
Y
S
E
E
P
A
G
E
T
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BGR3
1451
163208
T1360
H
S
A
V
L
E
S
T
G
D
V
E
L
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41877
1009
116656
S932
V
F
E
E
L
R
Q
S
V
R
M
A
P
Q
F
Sea Urchin
Strong. purpuratus
XP_781405
563
63991
R486
N
L
R
E
E
K
H
R
C
L
V
F
S
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.5
78.8
N.A.
73.4
N.A.
N.A.
49.9
N.A.
N.A.
44.4
N.A.
N.A.
N.A.
24.7
22.9
Protein Similarity:
100
N.A.
98.4
85.8
N.A.
82.3
N.A.
N.A.
63.8
N.A.
N.A.
60
N.A.
N.A.
N.A.
42.7
33.2
P-Site Identity:
100
N.A.
93.3
66.6
N.A.
60
N.A.
N.A.
6.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
20
26.6
P-Site Similarity:
100
N.A.
93.3
80
N.A.
73.3
N.A.
N.A.
26.6
N.A.
N.A.
40
N.A.
N.A.
N.A.
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
13
0
0
0
0
0
0
0
13
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
13
0
0
0
0
13
0
0
0
13
0
% D
% Glu:
0
13
25
63
13
13
0
13
13
0
0
13
13
25
0
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
0
13
0
0
13
% F
% Gly:
0
0
0
13
0
0
0
0
13
0
0
13
0
0
0
% G
% His:
13
0
0
0
13
0
13
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
63
0
0
0
0
0
0
0
25
0
% K
% Leu:
50
13
0
0
25
0
0
0
0
63
0
0
13
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
25
13
0
0
0
% M
% Asn:
13
0
0
0
38
0
0
0
13
0
0
0
0
0
0
% N
% Pro:
0
13
0
0
0
0
0
0
0
13
0
0
13
0
50
% P
% Gln:
0
0
0
0
0
0
13
0
0
0
0
0
0
25
0
% Q
% Arg:
0
0
13
0
0
13
0
13
0
13
0
0
13
0
0
% R
% Ser:
0
38
50
0
0
0
75
63
0
0
0
0
50
0
25
% S
% Thr:
0
0
0
0
0
0
0
13
0
0
38
38
0
13
0
% T
% Val:
25
0
0
13
0
0
0
0
13
0
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
38
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _