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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP6
All Species:
9.09
Human Site:
S185
Identified Species:
33.33
UniProt:
Q2NL67
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2NL67
NP_064599.2
630
71115
S185
S
P
I
P
K
S
P
S
F
P
I
I
Q
D
S
Chimpanzee
Pan troglodytes
XP_001151108
794
88940
C262
H
K
L
L
R
R
T
C
S
S
T
V
K
T
D
Rhesus Macaque
Macaca mulatta
XP_001093721
714
80586
Q243
E
R
F
G
L
G
H
Q
L
K
K
I
M
Q
T
Dog
Lupus familis
XP_853096
631
71224
S185
S
P
I
P
K
S
P
S
F
P
I
I
Q
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6P6P7
630
71157
S185
S
P
I
P
K
S
P
S
F
P
I
I
Q
D
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666929
619
69708
R185
G
G
T
I
K
K
F
R
A
G
L
S
I
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783307
627
70977
L198
N
T
S
R
G
R
T
L
T
I
P
I
S
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.1
46.5
99.8
N.A.
99.5
N.A.
N.A.
N.A.
N.A.
N.A.
77.6
N.A.
N.A.
N.A.
N.A.
47.4
Protein Similarity:
100
63.2
59.3
99.8
N.A.
99.6
N.A.
N.A.
N.A.
N.A.
N.A.
86.8
N.A.
N.A.
N.A.
N.A.
63
P-Site Identity:
100
0
6.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
13.3
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
43
15
% D
% Glu:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
15
0
0
0
15
0
43
0
0
0
0
29
0
% F
% Gly:
15
15
0
15
15
15
0
0
0
15
0
0
0
0
0
% G
% His:
15
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
43
15
0
0
0
0
0
15
43
72
15
0
0
% I
% Lys:
0
15
0
0
58
15
0
0
0
15
15
0
15
0
0
% K
% Leu:
0
0
15
15
15
0
0
15
15
0
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
43
0
43
0
0
43
0
0
43
15
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
15
0
0
0
0
43
15
0
% Q
% Arg:
0
15
0
15
15
29
0
15
0
0
0
0
0
0
0
% R
% Ser:
43
0
15
0
0
43
0
43
15
15
0
15
15
0
72
% S
% Thr:
0
15
15
0
0
0
29
0
15
0
15
0
0
15
15
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _