KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP6
All Species:
10.3
Human Site:
Y227
Identified Species:
37.78
UniProt:
Q2NL67
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2NL67
NP_064599.2
630
71115
Y227
P
K
V
E
V
F
G
Y
P
P
S
P
Q
A
G
Chimpanzee
Pan troglodytes
XP_001151108
794
88940
E387
S
K
T
E
L
F
K
E
P
N
A
E
G
R
R
Rhesus Macaque
Macaca mulatta
XP_001093721
714
80586
S289
L
F
S
T
L
R
R
S
P
S
Y
P
P
P
G
Dog
Lupus familis
XP_853096
631
71224
Y227
P
K
V
E
V
F
G
Y
P
P
S
P
Q
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6P6P7
630
71157
Y227
P
K
V
E
V
F
G
Y
P
P
S
P
Q
A
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666929
619
69708
L222
Q
E
L
R
V
T
R
L
M
S
R
S
M
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783307
627
70977
P235
H
G
N
D
P
L
P
P
V
I
H
L
H
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.1
46.5
99.8
N.A.
99.5
N.A.
N.A.
N.A.
N.A.
N.A.
77.6
N.A.
N.A.
N.A.
N.A.
47.4
Protein Similarity:
100
63.2
59.3
99.8
N.A.
99.6
N.A.
N.A.
N.A.
N.A.
N.A.
86.8
N.A.
N.A.
N.A.
N.A.
63
P-Site Identity:
100
26.6
20
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
40
26.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
15
0
0
43
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
0
58
0
0
0
15
0
0
0
15
0
0
0
% E
% Phe:
0
15
0
0
0
58
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
0
0
0
0
43
0
0
0
0
0
15
0
58
% G
% His:
15
0
0
0
0
0
0
0
0
0
15
0
15
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% I
% Lys:
0
58
0
0
0
0
15
0
0
0
0
0
0
0
0
% K
% Leu:
15
0
15
0
29
15
0
15
0
0
0
15
0
15
15
% L
% Met:
0
0
0
0
0
0
0
0
15
0
0
0
15
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
0
15
0
0
0
0
0
% N
% Pro:
43
0
0
0
15
0
15
15
72
43
0
58
15
15
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
0
0
43
0
0
% Q
% Arg:
0
0
0
15
0
15
29
0
0
0
15
0
0
15
15
% R
% Ser:
15
0
15
0
0
0
0
15
0
29
43
15
0
15
0
% S
% Thr:
0
0
15
15
0
15
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
43
0
58
0
0
0
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _