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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP6
All Species:
22.73
Human Site:
Y400
Identified Species:
83.33
UniProt:
Q2NL67
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2NL67
NP_064599.2
630
71115
Y400
R
E
M
T
Q
G
S
Y
L
E
I
K
K
Q
M
Chimpanzee
Pan troglodytes
XP_001151108
794
88940
Y563
R
E
M
T
Q
A
P
Y
L
E
I
K
K
Q
M
Rhesus Macaque
Macaca mulatta
XP_001093721
714
80586
Y483
R
E
M
T
Q
A
P
Y
L
E
I
K
K
Q
M
Dog
Lupus familis
XP_853096
631
71224
Y400
R
E
M
T
Q
G
S
Y
L
E
I
K
K
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q6P6P7
630
71157
Y400
R
E
M
T
Q
G
S
Y
L
E
I
K
K
Q
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666929
619
69708
Y391
R
E
I
T
Q
G
P
Y
V
E
I
K
K
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783307
627
70977
S405
T
D
M
L
A
A
G
S
V
T
D
M
K
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.1
46.5
99.8
N.A.
99.5
N.A.
N.A.
N.A.
N.A.
N.A.
77.6
N.A.
N.A.
N.A.
N.A.
47.4
Protein Similarity:
100
63.2
59.3
99.8
N.A.
99.6
N.A.
N.A.
N.A.
N.A.
N.A.
86.8
N.A.
N.A.
N.A.
N.A.
63
P-Site Identity:
100
86.6
86.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
43
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
0
0
0
15
0
0
0
0
% D
% Glu:
0
86
0
0
0
0
0
0
0
86
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
58
15
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
0
0
0
86
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
86
100
15
0
% K
% Leu:
0
0
0
15
0
0
0
0
72
0
0
0
0
0
0
% L
% Met:
0
0
86
0
0
0
0
0
0
0
0
15
0
0
86
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
43
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
86
0
0
0
0
0
0
0
0
86
15
% Q
% Arg:
86
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
43
15
0
0
0
0
0
0
0
% S
% Thr:
15
0
0
86
0
0
0
0
0
15
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
29
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _