KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSR1
All Species:
20
Human Site:
S49
Identified Species:
36.67
UniProt:
Q2NL82
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2NL82
NP_060598.3
804
91810
S49
K
K
V
R
K
E
L
S
R
V
D
Q
R
H
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086730
805
92092
S49
K
K
V
R
K
E
L
S
R
V
D
Q
R
H
R
Dog
Lupus familis
XP_852531
801
91987
S46
K
K
V
R
K
E
L
S
K
V
D
Q
R
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWD9
803
92087
S49
K
K
L
K
R
Q
L
S
R
I
D
Q
R
H
R
Rat
Rattus norvegicus
XP_002724564
804
92040
S49
K
K
L
K
K
Q
L
S
R
V
D
Q
R
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509532
723
82689
Q30
K
A
L
S
R
V
D
Q
R
H
R
A
G
Q
I
Chicken
Gallus gallus
XP_001234320
808
91988
N50
H
R
R
R
R
D
L
N
R
V
D
R
R
H
Q
Frog
Xenopus laevis
Q5XGY1
815
93592
R55
K
K
N
K
K
D
L
R
K
L
D
R
R
H
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP47
814
93699
R52
H
K
H
K
Q
Q
Q
R
K
E
Q
R
R
N
Q
Honey Bee
Apis mellifera
XP_624169
961
110510
G54
K
R
V
T
K
N
L
G
K
D
A
R
R
H
Q
Nematode Worm
Caenorhab. elegans
Q19329
785
89202
R52
R
S
A
H
S
T
H
R
T
I
S
K
D
A
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564480
793
89437
S40
G
R
I
G
K
S
D
S
N
Y
V
K
G
A
K
Baker's Yeast
Sacchar. cerevisiae
Q07381
788
90729
V49
T
G
K
P
D
K
Q
V
S
K
L
Q
R
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
88.1
N.A.
85.8
84.4
N.A.
70
68.6
65.5
N.A.
N.A.
44.7
41.9
39.9
N.A.
Protein Similarity:
100
N.A.
98.3
92.6
N.A.
91.2
90.5
N.A.
78.1
84.4
79.5
N.A.
N.A.
65.3
57.6
58.9
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
66.6
80
N.A.
13.3
46.6
46.6
N.A.
N.A.
13.3
40
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
86.6
86.6
N.A.
N.A.
60
66.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.8
51.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
0
8
8
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
16
16
0
0
8
54
0
8
0
0
% D
% Glu:
0
0
0
0
0
24
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
8
0
0
0
8
0
0
0
0
16
0
0
% G
% His:
16
0
8
8
0
0
8
0
0
8
0
0
0
62
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
16
0
0
0
0
8
% I
% Lys:
62
54
8
31
54
8
0
0
31
8
0
16
0
8
16
% K
% Leu:
0
0
24
0
0
0
62
0
0
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
8
8
0
0
0
0
8
8
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
24
16
8
0
0
8
47
0
8
24
% Q
% Arg:
8
24
8
31
24
0
0
24
47
0
8
31
77
0
47
% R
% Ser:
0
8
0
8
8
8
0
47
8
0
8
0
0
0
0
% S
% Thr:
8
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
31
0
0
8
0
8
0
39
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _