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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSR1
All Species:
12.12
Human Site:
Y459
Identified Species:
22.22
UniProt:
Q2NL82
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2NL82
NP_060598.3
804
91810
Y459
E
S
V
H
D
D
L
Y
D
K
K
V
D
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086730
805
92092
L459
G
E
S
V
H
D
G
L
Y
D
E
K
V
D
E
Dog
Lupus familis
XP_852531
801
91987
D457
S
V
H
D
D
L
Y
D
E
N
V
D
D
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWD9
803
92087
D459
S
V
R
D
D
L
Y
D
E
K
V
D
A
E
D
Rat
Rattus norvegicus
XP_002724564
804
92040
Y459
E
S
V
R
D
D
L
Y
D
E
K
V
D
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509532
723
82689
Y377
E
S
V
R
D
D
R
Y
D
E
E
L
D
E
E
Chicken
Gallus gallus
XP_001234320
808
91988
V460
T
M
T
V
S
E
C
V
R
D
D
Q
Y
D
E
Frog
Xenopus laevis
Q5XGY1
815
93592
S465
E
T
L
T
I
P
D
S
T
R
D
D
K
Y
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP47
814
93699
Q448
D
S
D
T
E
E
F
Q
D
T
V
S
V
A
S
Honey Bee
Apis mellifera
XP_624169
961
110510
Y456
S
E
V
P
D
E
R
Y
D
Q
N
I
D
M
T
Nematode Worm
Caenorhab. elegans
Q19329
785
89202
F426
T
T
A
S
E
M
M
F
D
D
G
I
D
E
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564480
793
89437
Q448
R
D
I
D
T
E
T
Q
N
E
S
E
M
V
D
Baker's Yeast
Sacchar. cerevisiae
Q07381
788
90729
E441
M
M
V
E
Q
D
N
E
E
V
A
G
D
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
88.1
N.A.
85.8
84.4
N.A.
70
68.6
65.5
N.A.
N.A.
44.7
41.9
39.9
N.A.
Protein Similarity:
100
N.A.
98.3
92.6
N.A.
91.2
90.5
N.A.
78.1
84.4
79.5
N.A.
N.A.
65.3
57.6
58.9
N.A.
P-Site Identity:
100
N.A.
13.3
20
N.A.
20
86.6
N.A.
66.6
6.6
6.6
N.A.
N.A.
13.3
33.3
20
N.A.
P-Site Similarity:
100
N.A.
26.6
26.6
N.A.
33.3
93.3
N.A.
86.6
20
33.3
N.A.
N.A.
33.3
53.3
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.8
51.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
8
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
24
47
39
8
16
47
24
16
24
54
16
31
% D
% Glu:
31
16
0
8
16
31
0
8
24
24
16
8
0
54
47
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
8
8
0
0
0
% G
% His:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
16
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
16
16
8
8
0
0
% K
% Leu:
0
0
8
0
0
16
16
8
0
0
0
8
0
0
0
% L
% Met:
8
16
0
0
0
8
8
0
0
0
0
0
8
8
0
% M
% Asn:
0
0
0
0
0
0
8
0
8
8
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
16
0
8
0
8
0
0
0
% Q
% Arg:
8
0
8
16
0
0
16
0
8
8
0
0
0
0
0
% R
% Ser:
24
31
8
8
8
0
0
8
0
0
8
8
0
0
8
% S
% Thr:
16
16
8
16
8
0
8
0
8
8
0
0
0
0
8
% T
% Val:
0
16
39
16
0
0
0
8
0
8
24
16
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
31
8
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _