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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPY19L1
All Species:
23.03
Human Site:
T439
Identified Species:
42.22
UniProt:
Q2PZI1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2PZI1
NP_056098.1
675
77319
T439
G
V
L
A
K
Q
Q
T
H
V
R
K
H
Q
F
Chimpanzee
Pan troglodytes
XP_001169062
675
77286
T439
G
V
L
A
K
Q
Q
T
H
V
R
K
H
Q
F
Rhesus Macaque
Macaca mulatta
XP_001105350
677
77367
T441
G
V
L
A
K
Q
Q
T
H
V
R
K
H
Q
F
Dog
Lupus familis
XP_539512
653
74982
T417
G
V
L
T
K
Q
Q
T
H
I
R
K
H
Q
F
Cat
Felis silvestris
Mouse
Mus musculus
A6X919
746
84169
T510
G
V
V
A
K
Q
R
T
H
T
R
K
Q
Q
F
Rat
Rattus norvegicus
XP_235970
746
84346
T510
G
V
I
A
N
Q
E
T
D
V
R
K
H
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508949
256
29083
T35
F
D
F
M
E
K
E
T
P
L
R
Y
T
K
T
Chicken
Gallus gallus
XP_418841
767
86447
Q531
W
T
F
S
Q
T
R
Q
H
E
R
E
E
R
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002868
730
82862
E489
Q
E
K
S
E
D
D
E
T
E
Q
S
H
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWR8
872
101079
V620
S
S
R
R
S
S
V
V
P
T
A
N
A
Q
I
Honey Bee
Apis mellifera
XP_394017
691
79722
P438
N
Y
K
I
K
G
Y
P
K
C
I
E
A
D
L
Nematode Worm
Caenorhab. elegans
P34413
683
77833
I446
L
W
R
N
S
E
E
I
G
E
N
G
E
I
L
Sea Urchin
Strong. purpuratus
XP_785579
669
76751
D436
N
D
D
I
P
A
K
D
E
L
E
V
R
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
96.3
93.9
N.A.
83.5
83.3
N.A.
30.3
67.2
N.A.
62.8
N.A.
20.7
38
41.4
53
Protein Similarity:
100
100
97.3
95.8
N.A.
87.4
87
N.A.
35.1
78
N.A.
75.7
N.A.
37.2
56.8
60.1
69.7
P-Site Identity:
100
100
100
86.6
N.A.
73.3
66.6
N.A.
13.3
13.3
N.A.
6.6
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
46.6
53.3
N.A.
26.6
N.A.
6.6
13.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
39
0
8
0
0
0
0
8
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
16
8
0
0
8
8
8
8
0
0
0
0
8
0
% D
% Glu:
0
8
0
0
16
8
24
8
8
24
8
16
16
0
0
% E
% Phe:
8
0
16
0
0
0
0
0
0
0
0
0
0
0
39
% F
% Gly:
47
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
47
0
0
0
47
0
0
% H
% Ile:
0
0
8
16
0
0
0
8
0
8
8
0
0
8
8
% I
% Lys:
0
0
16
0
47
8
8
0
8
0
0
47
0
8
0
% K
% Leu:
8
0
31
0
0
0
0
0
0
16
0
0
0
8
31
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
8
8
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
16
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
8
47
31
8
0
0
8
0
8
62
0
% Q
% Arg:
0
0
16
8
0
0
16
0
0
0
62
0
8
8
0
% R
% Ser:
8
8
0
16
16
8
0
0
0
0
0
8
0
0
0
% S
% Thr:
0
8
0
8
0
8
0
54
8
16
0
0
8
0
8
% T
% Val:
0
47
8
0
0
0
8
8
0
31
0
8
0
0
8
% V
% Trp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _