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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPV17L All Species: 7.58
Human Site: T174 Identified Species: 15.15
UniProt: Q2QL34 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2QL34 NP_001121895.1 196 22116 T174 S Q Q S G D G T F K S A F T I
Chimpanzee Pan troglodytes XP_520595 300 33787 R238 W A A V G E K R A Q E G A G R
Rhesus Macaque Macaca mulatta XP_001108380 196 22116 T174 S Q Q S G D G T L K S A F T I
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q99MS3 194 22161 D172 C F S Q Q S G D G T L Q S I F
Rat Rattus norvegicus Q5BK62 176 19609 H152 N F Y L V P L H Y R L A V V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q68F62 203 23327 E173 I R N R D I N E V T T R L L H
Zebra Danio Brachydanio rerio XP_691639 199 23191 T175 S R Q S G D G T A A V A L A W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097610 204 23183 V183 T K R Q S L P V A T K E I A T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q7YWV6 181 21290 V158 R V I L N Q V V A F F W N C Y
Sea Urchin Strong. purpuratus XP_788661 186 21219 A164 L P T S L R I A Y I A S L S F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06563 197 22897 Y174 V A I F W N T Y L S Y K N S K
Red Bread Mold Neurospora crassa Q7SCY7 172 19190 D149 N F K V V P L D H R V L F V N
Conservation
Percent
Protein Identity: 100 50 89.8 N.A. N.A. 77 30.1 N.A. N.A. N.A. 41.8 46.2 N.A. 29.8 N.A. 29.5 29.5
Protein Similarity: 100 57.3 92.3 N.A. N.A. 85.1 44.9 N.A. N.A. N.A. 61.5 62.8 N.A. 48.5 N.A. 43.8 46.9
P-Site Identity: 100 6.6 93.3 N.A. N.A. 6.6 6.6 N.A. N.A. N.A. 0 53.3 N.A. 0 N.A. 0 6.6
P-Site Similarity: 100 20 93.3 N.A. N.A. 6.6 26.6 N.A. N.A. N.A. 13.3 60 N.A. 20 N.A. 0 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.8 26
Protein Similarity: N.A. N.A. N.A. N.A. 47.7 41.3
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 0 0 0 0 9 34 9 9 34 9 17 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 9 25 0 17 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 9 0 0 9 9 0 0 0 % E
% Phe: 0 25 0 9 0 0 0 0 9 9 9 0 25 0 17 % F
% Gly: 0 0 0 0 34 0 34 0 9 0 0 9 0 9 0 % G
% His: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 9 % H
% Ile: 9 0 17 0 0 9 9 0 0 9 0 0 9 9 17 % I
% Lys: 0 9 9 0 0 0 9 0 0 17 9 9 0 0 9 % K
% Leu: 9 0 0 17 9 9 17 0 17 0 17 9 25 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 9 0 9 9 9 0 0 0 0 0 17 0 9 % N
% Pro: 0 9 0 0 0 17 9 0 0 0 0 0 0 0 0 % P
% Gln: 0 17 25 17 9 9 0 0 0 9 0 9 0 0 9 % Q
% Arg: 9 17 9 9 0 9 0 9 0 17 0 9 0 0 9 % R
% Ser: 25 0 9 34 9 9 0 0 0 9 17 9 9 17 0 % S
% Thr: 9 0 9 0 0 0 9 25 0 25 9 0 0 17 9 % T
% Val: 9 9 0 17 17 0 9 17 9 0 17 0 9 17 0 % V
% Trp: 9 0 0 0 9 0 0 0 0 0 0 9 0 0 9 % W
% Tyr: 0 0 9 0 0 0 0 9 17 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _