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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS4L2
All Species:
17.88
Human Site:
Y412
Identified Species:
49.17
UniProt:
Q2T9F4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2T9F4
NP_291025
439
48884
Y412
Q
Q
S
L
E
R
V
Y
S
L
Q
H
L
D
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092200
963
108141
Y622
Q
Q
S
L
E
R
V
Y
S
L
Q
H
L
D
P
Dog
Lupus familis
XP_534000
964
108247
Y623
Q
Q
S
L
E
R
V
Y
S
L
Q
H
L
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIM8
964
108174
Y623
Q
Q
S
L
E
R
V
Y
S
V
Q
H
L
D
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417220
941
105375
Y636
H
Q
S
L
E
R
V
Y
N
L
Q
H
L
D
P
Frog
Xenopus laevis
Q68F70
969
109237
H624
Q
L
S
L
E
R
V
H
N
L
Q
H
L
G
S
Zebra Danio
Brachydanio rerio
XP_001923719
978
109163
V631
N
F
L
Q
D
S
L
V
R
V
S
A
L
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623793
916
101959
E587
E
K
V
V
T
G
V
E
N
A
R
P
G
G
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198975
847
94130
G508
Q
T
L
D
K
L
K
G
L
D
G
L
S
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
42.2
41.7
N.A.
41.7
N.A.
N.A.
N.A.
42.1
37.6
37.2
N.A.
N.A.
24.3
N.A.
32.4
Protein Similarity:
100
N.A.
43.4
42.9
N.A.
42.9
N.A.
N.A.
N.A.
43.8
41.1
41.3
N.A.
N.A.
34.8
N.A.
39.9
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
N.A.
86.6
66.6
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
93.3
80
26.6
N.A.
N.A.
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
12
0
0
0
0
12
0
0
0
56
0
% D
% Glu:
12
0
0
0
67
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
12
0
0
12
0
12
23
0
% G
% His:
12
0
0
0
0
0
0
12
0
0
0
67
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
12
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
23
67
0
12
12
0
12
56
0
12
78
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
34
0
0
0
0
12
12
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
56
% P
% Gln:
67
56
0
12
0
0
0
0
0
0
67
0
0
12
0
% Q
% Arg:
0
0
0
0
0
67
0
0
12
0
12
0
0
0
12
% R
% Ser:
0
0
67
0
0
12
0
0
45
0
12
0
12
0
23
% S
% Thr:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
12
0
0
78
12
0
23
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _