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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYSND1
All Species:
12.12
Human Site:
S499
Identified Species:
38.1
UniProt:
Q2T9J0
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2T9J0
NP_001035363.1
566
59309
S499
N
L
L
G
I
I
T
S
N
T
R
D
N
N
T
Chimpanzee
Pan troglodytes
XP_001170770
566
59207
S499
N
L
L
G
I
I
T
S
N
T
R
D
N
N
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBA6
568
59047
S501
D
L
L
G
I
V
A
S
N
T
R
D
N
N
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232633
418
43285
L369
A
G
T
T
Y
P
H
L
N
F
C
I
P
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122182
521
56653
S459
E
L
L
G
I
V
S
S
N
T
R
D
Y
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611968
509
56443
C446
N
G
C
I
L
G
V
C
V
S
N
I
K
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002329829
716
77609
N612
M
I
G
L
V
T
S
N
A
R
H
G
G
G
T
Maize
Zea mays
NP_001170121
720
78313
N616
M
V
G
I
I
T
S
N
A
K
H
G
G
G
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
N.A.
N.A.
79.5
N.A.
N.A.
N.A.
36.2
N.A.
37.6
N.A.
24.9
N.A.
N.A.
N.A.
Protein Similarity:
100
98.5
N.A.
N.A.
N.A.
85.9
N.A.
N.A.
N.A.
45.7
N.A.
54.9
N.A.
40.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
6.6
N.A.
60
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
13.3
N.A.
73.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
24.3
23.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35.3
37.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
13
0
25
0
0
0
0
13
13
% A
% Cys:
0
0
13
0
0
0
0
13
0
0
13
0
0
0
0
% C
% Asp:
13
0
0
0
0
0
0
0
0
0
0
50
0
0
13
% D
% Glu:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% F
% Gly:
0
25
25
50
0
13
0
0
0
0
0
25
25
25
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
25
0
0
0
0
% H
% Ile:
0
13
0
25
63
25
0
0
0
0
0
25
0
13
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
13
0
0
13
0
0
% K
% Leu:
0
50
50
13
13
0
0
13
0
0
0
0
0
13
0
% L
% Met:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
38
0
0
0
0
0
0
25
63
0
13
0
38
38
0
% N
% Pro:
0
0
0
0
0
13
0
0
0
0
0
0
13
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
50
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
38
50
0
13
0
0
0
0
25
% S
% Thr:
0
0
13
13
0
25
25
0
0
50
0
0
0
0
50
% T
% Val:
0
13
0
0
13
25
13
0
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _