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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IAH1 All Species: 16.06
Human Site: S113 Identified Species: 27.18
UniProt: Q2TAA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAA2 NP_001034702.1 248 27599 S113 E Y A A N L K S M V Q Y L K S
Chimpanzee Pan troglodytes XP_001155356 223 25020 Y92 N L K S M V Q Y L K S V D I P
Rhesus Macaque Macaca mulatta XP_001084501 248 27552 S113 E Y A A N L K S M V Q Y L K S
Dog Lupus familis XP_852049 249 27669 S113 E Y V A N L K S M V Q Y L K S
Cat Felis silvestris
Mouse Mus musculus Q9DB29 249 27956 D113 E Y S A N L R D M V Q Y L R S
Rat Rattus norvegicus Q711G3 249 27986 D113 E Y S A N L R D M V Q Y L R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519510 105 11863
Chicken Gallus gallus XP_419943 249 27635 S113 E Y A A N L T S M V R Y L K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q503L4 238 26530 I106 F S E N L K D I V R F L V S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796067 180 19902 V49 A D N M K A I V N Y L E S N G
Poplar Tree Populus trichocarpa XP_002318054 242 27247 E107 K M V L H L K E C S P T M L V
Maize Zea mays NP_001152447 242 26569 F109 L R A I C A Y F K E R W P S T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6NMR9 241 27135 F108 N L R S I V S F L K N R W P Q
Baker's Yeast Sacchar. cerevisiae P41734 238 27328 S107 D N I R Q M V S L M K S Y H I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.9 98.7 90.3 N.A. 83.5 82.7 N.A. 33.8 70.6 N.A. 57.2 N.A. N.A. N.A. N.A. 31.4
Protein Similarity: 100 89.9 100 95.1 N.A. 92.7 90.7 N.A. 38.7 81.9 N.A. 74.1 N.A. N.A. N.A. N.A. 45.9
P-Site Identity: 100 0 100 93.3 N.A. 73.3 73.3 N.A. 0 86.6 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 26.6 100 93.3 N.A. 93.3 93.3 N.A. 0 93.3 N.A. 13.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: 40.7 41.9 N.A. 40.7 29.4 N.A.
Protein Similarity: 57.2 56 N.A. 57.6 44.7 N.A.
P-Site Identity: 13.3 6.6 N.A. 0 6.6 N.A.
P-Site Similarity: 33.3 26.6 N.A. 20 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 29 43 0 15 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 8 15 0 0 0 0 8 0 0 % D
% Glu: 43 0 8 0 0 0 0 8 0 8 0 8 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 15 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 8 8 8 0 8 8 0 0 0 0 0 8 8 % I
% Lys: 8 0 8 0 8 8 29 0 8 15 8 0 0 29 8 % K
% Leu: 8 15 0 8 8 50 0 0 22 0 8 8 43 8 0 % L
% Met: 0 8 0 8 8 8 0 0 43 8 0 0 8 0 0 % M
% Asn: 15 8 8 8 43 0 0 0 8 0 8 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 0 8 8 8 % P
% Gln: 0 0 0 0 8 0 8 0 0 0 36 0 0 0 8 % Q
% Arg: 0 8 8 8 0 0 15 0 0 8 15 8 0 15 0 % R
% Ser: 0 8 15 15 0 0 8 36 0 8 8 8 8 15 43 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 8 % T
% Val: 0 0 15 0 0 15 8 8 8 43 0 8 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % W
% Tyr: 0 43 0 0 0 0 8 8 0 8 0 43 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _