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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IAH1 All Species: 28.18
Human Site: S201 Identified Species: 47.69
UniProt: Q2TAA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAA2 NP_001034702.1 248 27599 S201 L S D G L H L S P K G N E F L
Chimpanzee Pan troglodytes XP_001155356 223 25020 P177 S D G L H L S P K G N E F L F
Rhesus Macaque Macaca mulatta XP_001084501 248 27552 S201 L S D G L H L S P K G N E F L
Dog Lupus familis XP_852049 249 27669 S202 L S D G L H L S P K G N E F L
Cat Felis silvestris
Mouse Mus musculus Q9DB29 249 27956 S202 L S D G L H L S P M G N E F L
Rat Rattus norvegicus Q711G3 249 27986 S202 L S D G L H L S P L G N E F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519510 105 11863 I59 D E N P K Q H I P L D E Y V E
Chicken Gallus gallus XP_419943 249 27635 S201 L S D G L H L S M K G N N F L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q503L4 238 26530 L191 S V Y L S D G L H L S D K G N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796067 180 19902 H134 R F L S D G L H L S A D G A G
Poplar Tree Populus trichocarpa XP_002318054 242 27247 L192 F L S D G L H L T P E G N A V
Maize Zea mays NP_001152447 242 26569 T195 L S D G L H F T P V G N K I L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6NMR9 241 27135 L193 C L W D G L H L S R V G N K V
Baker's Yeast Sacchar. cerevisiae P41734 238 27328 S192 L T D G L H F S G K G Y K I F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.9 98.7 90.3 N.A. 83.5 82.7 N.A. 33.8 70.6 N.A. 57.2 N.A. N.A. N.A. N.A. 31.4
Protein Similarity: 100 89.9 100 95.1 N.A. 92.7 90.7 N.A. 38.7 81.9 N.A. 74.1 N.A. N.A. N.A. N.A. 45.9
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. 6.6 86.6 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 0 100 100 N.A. 93.3 93.3 N.A. 13.3 86.6 N.A. 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 40.7 41.9 N.A. 40.7 29.4 N.A.
Protein Similarity: 57.2 56 N.A. 57.6 44.7 N.A.
P-Site Identity: 0 66.6 N.A. 0 53.3 N.A.
P-Site Similarity: 6.6 80 N.A. 13.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 8 0 0 15 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 58 15 8 8 0 0 0 0 8 15 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 8 15 36 0 8 % E
% Phe: 8 8 0 0 0 0 15 0 0 0 0 0 8 43 15 % F
% Gly: 0 0 8 58 15 8 8 0 8 8 58 15 8 8 8 % G
% His: 0 0 0 0 8 58 22 8 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 15 0 % I
% Lys: 0 0 0 0 8 0 0 0 8 36 0 0 22 8 0 % K
% Leu: 58 15 8 15 58 22 50 22 8 22 0 0 0 8 50 % L
% Met: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 8 50 22 0 8 % N
% Pro: 0 0 0 8 0 0 0 8 50 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 15 50 8 8 8 0 8 50 8 8 8 0 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 8 8 0 0 0 0 0 0 % T
% Val: 0 8 0 0 0 0 0 0 0 8 8 0 0 8 15 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _