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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IAH1 All Species: 14.85
Human Site: T182 Identified Species: 25.13
UniProt: Q2TAA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAA2 NP_001034702.1 248 27599 T182 T D V L D L W T L M Q D S Q D
Chimpanzee Pan troglodytes XP_001155356 223 25020 L158 D V L D L W T L M Q D S Q D F
Rhesus Macaque Macaca mulatta XP_001084501 248 27552 T182 T D V L D L W T L M Q D S Q D
Dog Lupus familis XP_852049 249 27669 L183 D V L D L W T L M Q E D T Q D
Cat Felis silvestris
Mouse Mus musculus Q9DB29 249 27956 L183 D V L D L W T L M Q K D S Q D
Rat Rattus norvegicus Q711G3 249 27986 L183 D V L D L W T L M Q K D N Q D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519510 105 11863 T40 A E N P V A V T I F F G A N D
Chicken Gallus gallus XP_419943 249 27635 T182 T D V L D L W T L M Q K D Q D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q503L4 238 26530 L172 S G V D V L D L W T L M Q K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796067 180 19902 W115 D V K V I D I W T A M Q K E E
Poplar Tree Populus trichocarpa XP_002318054 242 27247 S173 I R A I D L W S K M Q G T D G
Maize Zea mays NP_001152447 242 26569 K176 P V I D I W T K M Q E F P D W
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6NMR9 241 27135 S174 I S V T D L W S K M Q Q I P N
Baker's Yeast Sacchar. cerevisiae P41734 238 27328 F173 F V A L N K A F Q Q E G G D A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.9 98.7 90.3 N.A. 83.5 82.7 N.A. 33.8 70.6 N.A. 57.2 N.A. N.A. N.A. N.A. 31.4
Protein Similarity: 100 89.9 100 95.1 N.A. 92.7 90.7 N.A. 38.7 81.9 N.A. 74.1 N.A. N.A. N.A. N.A. 45.9
P-Site Identity: 100 0 100 20 N.A. 26.6 20 N.A. 13.3 86.6 N.A. 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 13.3 100 46.6 N.A. 46.6 46.6 N.A. 33.3 86.6 N.A. 33.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 40.7 41.9 N.A. 40.7 29.4 N.A.
Protein Similarity: 57.2 56 N.A. 57.6 44.7 N.A.
P-Site Identity: 33.3 0 N.A. 40 6.6 N.A.
P-Site Similarity: 53.3 20 N.A. 53.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 15 0 0 8 8 0 0 8 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 36 22 0 43 36 8 8 0 0 0 8 36 8 29 58 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 22 0 0 8 8 % E
% Phe: 8 0 0 0 0 0 0 8 0 8 8 8 0 0 8 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 0 22 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 8 8 15 0 8 0 8 0 0 0 8 0 0 % I
% Lys: 0 0 8 0 0 8 0 8 15 0 15 8 8 8 0 % K
% Leu: 0 0 29 29 29 43 0 36 22 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 36 36 8 8 0 0 0 % M
% Asn: 0 0 8 0 8 0 0 0 0 0 0 0 8 8 8 % N
% Pro: 8 0 0 8 0 0 0 0 0 0 0 0 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 43 36 15 15 43 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 8 0 0 0 0 0 15 0 0 0 8 22 0 0 % S
% Thr: 22 0 0 8 0 0 36 29 8 8 0 0 15 0 0 % T
% Val: 0 50 36 8 15 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 36 36 8 8 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _