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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IAH1
All Species:
18.18
Human Site:
Y229
Identified Species:
30.77
UniProt:
Q2TAA2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2TAA2
NP_001034702.1
248
27599
Y229
S
L
P
L
L
L
P
Y
W
R
D
V
A
E
A
Chimpanzee
Pan troglodytes
XP_001155356
223
25020
W205
L
P
L
L
L
P
Y
W
R
D
V
A
E
A
K
Rhesus Macaque
Macaca mulatta
XP_001084501
248
27552
Y229
S
L
P
L
L
L
P
Y
W
R
D
V
A
E
A
Dog
Lupus familis
XP_852049
249
27669
Y230
S
L
P
L
L
L
P
Y
W
R
D
V
A
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB29
249
27956
Y230
S
L
P
W
L
L
P
Y
W
K
D
V
E
E
A
Rat
Rattus norvegicus
Q711G3
249
27986
D230
S
L
P
R
L
L
P
D
W
K
D
V
E
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519510
105
11863
L87
V
P
G
N
R
V
I
L
I
T
P
P
P
L
C
Chicken
Gallus gallus
XP_419943
249
27635
Y229
A
L
P
S
L
L
P
Y
W
R
D
V
D
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q503L4
238
26530
I219
R
V
S
D
L
P
F
I
L
P
Y
W
G
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796067
180
19902
F162
T
S
S
L
S
E
Q
F
P
D
W
S
E
V
D
Poplar Tree
Populus trichocarpa
XP_002318054
242
27247
Y220
L
S
A
E
D
M
P
Y
D
F
P
H
H
S
E
Maize
Zea mays
NP_001152447
242
26569
S223
F
S
Q
E
R
L
P
S
D
L
P
L
F
H
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6NMR9
241
27135
V221
I
G
A
E
D
L
A
V
D
L
P
L
I
E
D
Baker's Yeast
Sacchar. cerevisiae
P41734
238
27328
Q220
Q
Y
H
P
K
N
M
Q
Y
K
L
K
D
W
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
98.7
90.3
N.A.
83.5
82.7
N.A.
33.8
70.6
N.A.
57.2
N.A.
N.A.
N.A.
N.A.
31.4
Protein Similarity:
100
89.9
100
95.1
N.A.
92.7
90.7
N.A.
38.7
81.9
N.A.
74.1
N.A.
N.A.
N.A.
N.A.
45.9
P-Site Identity:
100
13.3
100
100
N.A.
80
66.6
N.A.
0
66.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
86.6
73.3
N.A.
6.6
73.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
40.7
41.9
N.A.
40.7
29.4
N.A.
Protein Similarity:
57.2
56
N.A.
57.6
44.7
N.A.
P-Site Identity:
13.3
13.3
N.A.
13.3
0
N.A.
P-Site Similarity:
20
20
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
0
0
8
0
0
0
0
8
22
8
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
8
15
0
0
8
22
15
43
0
15
8
15
% D
% Glu:
0
0
0
22
0
8
0
0
0
0
0
0
29
43
15
% E
% Phe:
8
0
0
0
0
0
8
8
0
8
0
0
8
0
0
% F
% Gly:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
8
8
0
% H
% Ile:
8
0
0
0
0
0
8
8
8
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
22
0
8
0
0
8
% K
% Leu:
15
43
8
36
58
58
0
8
8
15
8
15
0
8
0
% L
% Met:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
43
8
0
15
58
0
8
8
29
8
8
8
0
% P
% Gln:
8
0
8
0
0
0
8
8
0
0
0
0
0
0
8
% Q
% Arg:
8
0
0
8
15
0
0
0
8
29
0
0
0
0
8
% R
% Ser:
36
22
15
8
8
0
0
8
0
0
0
8
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% T
% Val:
8
8
0
0
0
8
0
8
0
0
8
43
0
8
8
% V
% Trp:
0
0
0
8
0
0
0
8
43
0
8
8
0
8
0
% W
% Tyr:
0
8
0
0
0
0
8
43
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _