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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG11 All Species: 5.76
Human Site: S333 Identified Species: 10.56
UniProt: Q2TAA5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAA5 NP_001004127 492 55651 S333 L N K K M V E S P P S L K L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q3TZM9 492 55252 L333 L N E K A A E L G H S L K L V
Rat Rattus norvegicus NP_001101871 492 55364 S333 L N E K A A E S R H S L K L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513294 523 57552 M364 L G K E A A K M L P S L K L V
Chicken Gallus gallus XP_417074 491 55589 Q332 L K E K R L R Q Q L S L K L I
Frog Xenopus laevis Q08B22 486 54690 Q329 L E K K T A E Q R A K L K L I
Zebra Danio Brachydanio rerio Q7ZW24 500 56604 G337 R K E A E P A G R E A V K L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649340 475 54535 L315 L L A Q D E A L W N Q I K L V
Honey Bee Apis mellifera XP_624912 516 60062 I353 R S I V K E E I W E K V R L I
Nematode Worm Caenorhab. elegans P53993 470 53628 M312 V K E P L E K M G Y N V E L C
Sea Urchin Strong. purpuratus XP_787277 476 52891 E317 M N K L T V D E K S V V R L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53954 548 63125 S338 F L K N L P D S V S P I K L I
Red Bread Mold Neurospora crassa Q8X092 556 62514 A388 F L K S G S E A A R D A K L V
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 86.1 86.7 N.A. 73.8 72.7 67.4 63.2 N.A. 48.7 47 43.7 54.6
Protein Similarity: 100 N.A. N.A. N.A. N.A. 92.2 92.6 N.A. 82.5 83.7 80.6 78.1 N.A. 65.8 64.7 62.2 71.5
P-Site Identity: 100 N.A. N.A. N.A. N.A. 60 66.6 N.A. 53.3 40 46.6 20 N.A. 26.6 13.3 6.6 26.6
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 66.6 73.3 N.A. 66.6 60 53.3 40 N.A. 40 40 53.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.6 38.1
Protein Similarity: N.A. N.A. N.A. N.A. 53.6 55
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 24 31 16 8 8 8 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 8 0 16 0 0 0 8 0 0 0 0 % D
% Glu: 0 8 39 8 8 24 47 8 0 16 0 0 8 0 8 % E
% Phe: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 8 0 0 8 16 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 8 0 0 0 16 0 0 31 % I
% Lys: 0 24 47 39 8 0 16 0 8 0 16 0 77 0 0 % K
% Leu: 54 24 0 8 16 8 0 16 8 8 0 47 0 100 0 % L
% Met: 8 0 0 0 8 0 0 16 0 0 0 0 0 0 0 % M
% Asn: 0 31 0 8 0 0 0 0 0 8 8 0 0 0 0 % N
% Pro: 0 0 0 8 0 16 0 0 8 16 8 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 16 8 0 8 0 0 0 0 % Q
% Arg: 16 0 0 0 8 0 8 0 24 8 0 0 16 0 0 % R
% Ser: 0 8 0 8 0 8 0 24 0 16 39 0 0 0 0 % S
% Thr: 0 0 0 0 16 0 0 0 0 0 0 0 0 0 0 % T
% Val: 8 0 0 8 0 16 0 0 8 0 8 31 0 0 54 % V
% Trp: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _