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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG11 All Species: 11.52
Human Site: S466 Identified Species: 21.11
UniProt: Q2TAA5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAA5 NP_001004127 492 55651 S466 K R L Q I R K S A R A S V S R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q3TZM9 492 55252 N466 E R L Q I R K N A R A S I S R
Rat Rattus norvegicus NP_001101871 492 55364 T466 K R L R I R E T A R A S L S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513294 523 57552 N497 E R L Q I R R N A R Q S V S R
Chicken Gallus gallus XP_417074 491 55589 S465 K R L E I R E S A R Q S V C R
Frog Xenopus laevis Q08B22 486 54690 N460 Q R L S I R Q N A R L S V G R
Zebra Danio Brachydanio rerio Q7ZW24 500 56604 R470 T R L E M R R R A R L S V S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649340 475 54535 A447 E M N G I R N A A R A S V E R
Honey Bee Apis mellifera XP_624912 516 60062 V486 D R N A I R T V A R A S V N R
Nematode Worm Caenorhab. elegans P53993 470 53628 Y445 K R N D T R K Y A R K S L T R
Sea Urchin Strong. purpuratus XP_787277 476 52891 A450 E R M K I R L A A R S S V D R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53954 548 63125 N513 L R V M G A R N Q Q Y S L Y K
Red Bread Mold Neurospora crassa Q8X092 556 62514 R521 Y A V R L R A R K S A K R F T
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 86.1 86.7 N.A. 73.8 72.7 67.4 63.2 N.A. 48.7 47 43.7 54.6
Protein Similarity: 100 N.A. N.A. N.A. N.A. 92.2 92.6 N.A. 82.5 83.7 80.6 78.1 N.A. 65.8 64.7 62.2 71.5
P-Site Identity: 100 N.A. N.A. N.A. N.A. 80 73.3 N.A. 73.3 73.3 60 60 N.A. 53.3 60 53.3 53.3
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 100 100 N.A. 93.3 86.6 80 80 N.A. 66.6 66.6 66.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.6 38.1
Protein Similarity: N.A. N.A. N.A. N.A. 53.6 55
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 8 8 16 85 0 47 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 31 0 0 16 0 0 16 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 8 8 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 70 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 31 0 0 8 0 0 24 0 8 0 8 8 0 0 8 % K
% Leu: 8 0 54 0 8 0 8 0 0 0 16 0 24 0 0 % L
% Met: 0 8 8 8 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 24 0 0 0 8 31 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 24 0 0 8 0 8 8 16 0 0 0 0 % Q
% Arg: 0 85 0 16 0 93 24 16 0 85 0 0 8 0 85 % R
% Ser: 0 0 0 8 0 0 0 16 0 8 8 93 0 39 0 % S
% Thr: 8 0 0 0 8 0 8 8 0 0 0 0 0 8 8 % T
% Val: 0 0 16 0 0 0 0 8 0 0 0 0 62 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 8 0 0 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _