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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG11 All Species: 41.82
Human Site: Y199 Identified Species: 76.67
UniProt: Q2TAA5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2TAA5 NP_001004127 492 55651 Y199 Q V G S Y V H Y P T I S T D M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q3TZM9 492 55252 Y199 R V G S Y V H Y P T I S T D M
Rat Rattus norvegicus NP_001101871 492 55364 Y199 R V G S Y V H Y P T I S T D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513294 523 57552 Y227 R V G C Y V H Y P T I S T D M
Chicken Gallus gallus XP_417074 491 55589 Y198 R V G C Y V H Y P T I S T D M
Frog Xenopus laevis Q08B22 486 54690 Y195 H V G C Y V H Y P T I S M D M
Zebra Danio Brachydanio rerio Q7ZW24 500 56604 Y197 Q V G S Y V H Y P T I S T D M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649340 475 54535 Y181 K V G C Y V H Y P V I S T D M
Honey Bee Apis mellifera XP_624912 516 60062 Y218 R V A T Y T H Y P T I S T D M
Nematode Worm Caenorhab. elegans P53993 470 53628 Y177 K V V A Y V H Y P T I S C D M
Sea Urchin Strong. purpuratus XP_787277 476 52891 Y183 R V G C Y V H Y P T I S T D M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53954 548 63125 H213 I P I V T Y T H Y P I M S K D
Red Bread Mold Neurospora crassa Q8X092 556 62514 H237 V P T A A Y V H Y P T I S T D
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 86.1 86.7 N.A. 73.8 72.7 67.4 63.2 N.A. 48.7 47 43.7 54.6
Protein Similarity: 100 N.A. N.A. N.A. N.A. 92.2 92.6 N.A. 82.5 83.7 80.6 78.1 N.A. 65.8 64.7 62.2 71.5
P-Site Identity: 100 N.A. N.A. N.A. N.A. 93.3 93.3 N.A. 86.6 86.6 80 100 N.A. 80 73.3 73.3 86.6
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 100 100 N.A. 93.3 93.3 80 100 N.A. 86.6 86.6 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.6 38.1
Protein Similarity: N.A. N.A. N.A. N.A. 53.6 55
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 16 8 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 39 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 85 16 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 85 16 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 0 0 0 0 0 0 93 8 0 0 0 % I
% Lys: 16 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 85 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 16 0 0 0 0 0 0 85 16 0 0 0 0 0 % P
% Gln: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 31 0 0 0 0 0 0 0 85 16 0 0 % S
% Thr: 0 0 8 8 8 8 8 0 0 77 8 0 70 8 0 % T
% Val: 8 85 8 8 0 77 8 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 85 16 0 85 16 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _